FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891481208> ?p ?o ?g. }

• W2891481208 endingPage "18237" @default.
• W2891481208 startingPage "18228" @default.
• W2891481208 abstract "Natural polymers are widely used in biomedical applications because of their numerous effects. Especially, plant-derived natural polymers extracted from cell walls, especially wood, which is abundant, inexpensive and nontoxic to cells, have high mechanical strength to retain their turgor pressure. Plant-derived polymers are also unaffected by enzymes present in the human body, having a strong possibility to create a polymeric structure that releases drugs only exactly where needed. Therefore, plant-derived polymers are suitable for use in drug delivery systems (DDS) as they have durability with few drug leakage issues in the body. Here, to improve drug incorporation and release efficiency, we prepared a multilayer nanofilm from tannic acid (TA) and lignin extracted from plants and wood. We used a strategy involving film degradation by tannase and laccase, which are not present in humans, to depolymerize TA and lignin, respectively. The TA and lignin film was highly stable for 7 days at pH 3-7 and was readily degraded after enzyme treatment. We also observed controllable drug release and anticancer effect from the TA and lignin hollow carriers depending on enzymatic activity. By taking advantage of plant-derived polymers and non-toxic enzymatic reactions, we have demonstrated the film growth and degradation mechanism in depth and explored their use in a smart DDS with easily controlled release kinetics, which is useful as a DDS platform." @default.
• W2891481208 created "2018-09-27" @default.
• W2891481208 creator A5016039810 @default.
• W2891481208 creator A5036186277 @default.
• W2891481208 creator A5083906433 @default.
• W2891481208 date "2018-01-01" @default.
• W2891481208 modified "2023-10-15" @default.
• W2891481208 title "Controllable drug release from nano-layered hollow carrier by non-human enzyme" @default.
• W2891481208 cites W1491373961 @default.
• W2891481208 cites W1501383064 @default.
• W2891481208 cites W1964661943 @default.
• W2891481208 cites W1975394561 @default.
• W2891481208 cites W1981465464 @default.
• W2891481208 cites W1981783442 @default.
• W2891481208 cites W1981860292 @default.
• W2891481208 cites W1987177290 @default.
• W2891481208 cites W1992279584 @default.
• W2891481208 cites W1997144768 @default.
• W2891481208 cites W2000617155 @default.
• W2891481208 cites W2005172316 @default.
• W2891481208 cites W2015341486 @default.
• W2891481208 cites W2017420365 @default.
• W2891481208 cites W2026477931 @default.
• W2891481208 cites W2027060219 @default.
• W2891481208 cites W2032691932 @default.
• W2891481208 cites W2043411268 @default.
• W2891481208 cites W2047901084 @default.
• W2891481208 cites W2048829256 @default.
• W2891481208 cites W2052257620 @default.
• W2891481208 cites W2052883454 @default.
• W2891481208 cites W2054796077 @default.
• W2891481208 cites W2057420831 @default.
• W2891481208 cites W2062759615 @default.
• W2891481208 cites W2070578413 @default.
• W2891481208 cites W2074457309 @default.
• W2891481208 cites W2077928856 @default.
• W2891481208 cites W2091668571 @default.
• W2891481208 cites W2094334681 @default.
• W2891481208 cites W2097594005 @default.
• W2891481208 cites W2100681906 @default.
• W2891481208 cites W2107357268 @default.
• W2891481208 cites W2115584603 @default.
• W2891481208 cites W2117208350 @default.
• W2891481208 cites W2127225888 @default.
• W2891481208 cites W2135569465 @default.
• W2891481208 cites W2154659743 @default.
• W2891481208 cites W2155770305 @default.
• W2891481208 cites W2259682376 @default.
• W2891481208 cites W2268907291 @default.
• W2891481208 cites W2279377674 @default.
• W2891481208 cites W2290025845 @default.
• W2891481208 cites W2294095488 @default.
• W2891481208 cites W2316508377 @default.
• W2891481208 cites W2317055602 @default.
• W2891481208 cites W2405536096 @default.
• W2891481208 cites W2407465238 @default.
• W2891481208 cites W2410611620 @default.
• W2891481208 cites W2438292910 @default.
• W2891481208 cites W2462767068 @default.
• W2891481208 cites W2512463754 @default.
• W2891481208 cites W2559706090 @default.
• W2891481208 cites W2579338963 @default.
• W2891481208 cites W2587546550 @default.
• W2891481208 cites W2597772815 @default.
• W2891481208 cites W2609970229 @default.
• W2891481208 cites W2611404157 @default.
• W2891481208 cites W2733602250 @default.
• W2891481208 cites W2748364108 @default.
• W2891481208 cites W2782907625 @default.
• W2891481208 cites W2800000734 @default.
• W2891481208 doi "https://doi.org/10.1039/c8nr05269g" @default.
• W2891481208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30232482" @default.
• W2891481208 hasPublicationYear "2018" @default.
• W2891481208 type Work @default.
• W2891481208 sameAs 2891481208 @default.
• W2891481208 citedByCount "21" @default.
• W2891481208 countsByYear W28914812082019 @default.
• W2891481208 countsByYear W28914812082020 @default.
• W2891481208 countsByYear W28914812082021 @default.
• W2891481208 countsByYear W28914812082022 @default.
• W2891481208 countsByYear W28914812082023 @default.
• W2891481208 crossrefType "journal-article" @default.
• W2891481208 hasAuthorship W2891481208A5016039810 @default.
• W2891481208 hasAuthorship W2891481208A5036186277 @default.
• W2891481208 hasAuthorship W2891481208A5083906433 @default.
• W2891481208 hasConcept C118552586 @default.
• W2891481208 hasConcept C127413603 @default.
• W2891481208 hasConcept C15744967 @default.
• W2891481208 hasConcept C159985019 @default.
• W2891481208 hasConcept C171250308 @default.
• W2891481208 hasConcept C178790620 @default.
• W2891481208 hasConcept C181199279 @default.
• W2891481208 hasConcept C185592680 @default.
• W2891481208 hasConcept C192562407 @default.
• W2891481208 hasConcept C2779679103 @default.
• W2891481208 hasConcept C2779820397 @default.
• W2891481208 hasConcept C2780035454 @default.
• W2891481208 hasConcept C2781052789 @default.

• next