Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891494815> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2891494815 abstract "10117 Background: Breast cancer related lymphedema (BCRL) represents a major side effect that can significantly impact quality of life. Current guidelines support prospective surveillance to allow for early diagnosis and treatment of BCRL at a subclinical, reversible stage. This current large, single institution experience evaluated the use of bioimpedance spectroscopy (BIS) to monitor patients for the development and treatment of BCRL. Methods: From April 2010 through Nov 2016, 596 patients (79.6% with high-risk features) were evaluated with BIS.Patients received a pre-operative baseline L-Dex measurement and post-operatively at regular intervals. Elevated L-Dex scores were defined as an increase of ≥10 points above baseline (considered subclinical BCRL). Intervention then consisted of applying an over the counter (OTC) sleeve for 4 weeks followed by re-evaluation. The need for complete decongestive physiotherapy (CDP) represented a surrogate for the development of clinically significant, chronic BCRL. Results: Median follow-up for all patients was 17 months. Seventy-three patients (12%) developed an elevated L-Dex score with axillary lymph node dissection (ALND) (p < 0.001), taxanes (p = 0.008), and (regional nodal irradiation (RNI) (p < 0.001) associated. At last follow-up, only 18 patients (3%) had unresolved clinically significant BCRL requiring CDP. Mastectomy (p = 0.02), ALND (p < 0.001), taxanes (p = 0.05), and RNI (p < 0.001) were associated with requiring CDP. Conclusions: Our results demonstrate that prospective monitoring using BIS, with intervention (using a simple OTC sleeve for 4 weeks) triggered by a ≥10-point L-Dex elevation, resulted in only a 3% rate of chronic, clinically significant BCRL. These results are lower than reported in contemporary studies and validate recent guidelines supporting prospective screening and intervention for BCRL." @default.
- W2891494815 created "2018-09-27" @default.
- W2891494815 creator A5012253002 @default.
- W2891494815 creator A5016407136 @default.
- W2891494815 creator A5026403379 @default.
- W2891494815 creator A5064398705 @default.
- W2891494815 date "2017-05-20" @default.
- W2891494815 modified "2023-09-22" @default.
- W2891494815 title "Reducing chronic breast cancer related lymphedema utilizing a program of prospective surveillance with bioimpedance spectroscopy (BIS)." @default.
- W2891494815 doi "https://doi.org/10.1200/jco.2017.35.15_suppl.10117" @default.
- W2891494815 hasPublicationYear "2017" @default.
- W2891494815 type Work @default.
- W2891494815 sameAs 2891494815 @default.
- W2891494815 citedByCount "1" @default.
- W2891494815 countsByYear W28914948152018 @default.
- W2891494815 crossrefType "journal-article" @default.
- W2891494815 hasAuthorship W2891494815A5012253002 @default.
- W2891494815 hasAuthorship W2891494815A5016407136 @default.
- W2891494815 hasAuthorship W2891494815A5026403379 @default.
- W2891494815 hasAuthorship W2891494815A5064398705 @default.
- W2891494815 hasConcept C121608353 @default.
- W2891494815 hasConcept C126322002 @default.
- W2891494815 hasConcept C143998085 @default.
- W2891494815 hasConcept C188816634 @default.
- W2891494815 hasConcept C2781392513 @default.
- W2891494815 hasConcept C530470458 @default.
- W2891494815 hasConcept C71924100 @default.
- W2891494815 hasConceptScore W2891494815C121608353 @default.
- W2891494815 hasConceptScore W2891494815C126322002 @default.
- W2891494815 hasConceptScore W2891494815C143998085 @default.
- W2891494815 hasConceptScore W2891494815C188816634 @default.
- W2891494815 hasConceptScore W2891494815C2781392513 @default.
- W2891494815 hasConceptScore W2891494815C530470458 @default.
- W2891494815 hasConceptScore W2891494815C71924100 @default.
- W2891494815 hasLocation W28914948151 @default.
- W2891494815 hasOpenAccess W2891494815 @default.
- W2891494815 hasPrimaryLocation W28914948151 @default.
- W2891494815 hasRelatedWork W2110175289 @default.
- W2891494815 hasRelatedWork W2248481921 @default.
- W2891494815 hasRelatedWork W2315209748 @default.
- W2891494815 hasRelatedWork W2579742505 @default.
- W2891494815 hasRelatedWork W2605443078 @default.
- W2891494815 hasRelatedWork W2606498983 @default.
- W2891494815 hasRelatedWork W2607701022 @default.
- W2891494815 hasRelatedWork W2766675563 @default.
- W2891494815 hasRelatedWork W2789390410 @default.
- W2891494815 hasRelatedWork W2804257929 @default.
- W2891494815 hasRelatedWork W2809801362 @default.
- W2891494815 hasRelatedWork W2891756921 @default.
- W2891494815 hasRelatedWork W2914994601 @default.
- W2891494815 hasRelatedWork W2915460331 @default.
- W2891494815 hasRelatedWork W2994281903 @default.
- W2891494815 hasRelatedWork W3020218203 @default.
- W2891494815 hasRelatedWork W3027922657 @default.
- W2891494815 hasRelatedWork W3202123450 @default.
- W2891494815 hasRelatedWork W564962534 @default.
- W2891494815 hasRelatedWork W3113301216 @default.
- W2891494815 isParatext "false" @default.
- W2891494815 isRetracted "false" @default.
- W2891494815 magId "2891494815" @default.
- W2891494815 workType "article" @default.