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- W2891512801 abstract "In this chapter the basic principles of sample size calculation are discussed. The chapter also reviews the impact of sample size calculation on the study results, the parameters needed, and ways this calculation can be performed by researchers. Over- and underestimation of sample size for any study can have significant effects for the study participants, thus ensuring its adequacy is of critical importance. Setting values for alpha (level of significance) and beta (power) should be informed by the specific research goals and study hypothesis. A priori effect size estimation is challenging and can be done in various ways, which are addressed in this chapter. The chapter concludes with examples and references of sources that can be used for sample size calculation." @default.
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- W2891512801 date "2018-03-01" @default.
- W2891512801 modified "2023-09-27" @default.
- W2891512801 title "Sample Size Calculation" @default.
- W2891512801 doi "https://doi.org/10.1093/med/9780199324491.003.0011" @default.
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