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• W2891512849 abstract "In recent researches, high expression of nesfatin-1/nucleobindin-2 (NUCB2) is linked to poor prognosis in prostate and colon cancer due to the enhancement in proliferation, migration, and invasion. However, the role of nesfatin-1 in bladder cancer is not clear. In this study, we examined the expression of NUCB2 in bladder cancer using immunohistochemistry and observed that its high expression was associated with recurrence and metastasis. In addition, the transwell assay and wound healing assay showed that cell migration and invasion were decreased with NUCB2 knockdown in T24 and 5637 cells. In vivo, tumor growth and metastasis were inhibited with shRNA treatment in T24 cells. Those results showed that NUCB2 played an important role in bladder cancer and could be considered a potent prognostic factor in bladder cancer." @default.
• W2891512849 created "2018-09-27" @default.
• W2891512849 creator A5033875227 @default.
• W2891512849 creator A5063399027 @default.
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• W2891512849 date "2018-09-19" @default.
• W2891512849 modified "2023-10-18" @default.
• W2891512849 title "Nesfatin-1/Nucleobindin-2 Is a Potent Prognostic Marker and Enhances Cell Proliferation, Migration, and Invasion in Bladder Cancer" @default.
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• W2891512849 doi "https://doi.org/10.1155/2018/4272064" @default.
• W2891512849 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6169241" @default.
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