Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891517346> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2891517346 abstract "ABSTRACT: The present study aimed to evaluate the use of aqueous wheat extracts as an adjunct to antineoplastic therapy with carboplatin. In this study, 32 rats were used which were randomly distributed into 4 groups: G1 - negative control; G2 - control treated with physiological solution; G3 - animals treated with aqueous extract of wheat in the concentration of 100mg/kg; G4 - animals treated with aqueous wheat extract at the concentration of 400mg/kg; 300mg/m² of carboplatin was administered intraperitoneally at day 0 in animals from groups G2, G3, and G4, whereas 1ml of physiological solution was administered by the same route in animals from group G1. Animals were treated daily for 21 days by orogastric gavage according to their respective experimental group. Blood was collected from animals on days 3, 7 and 21 for complete blood count (CBC), biochemistry, and measurement of paraoxonase 1 (PON1) activity. On day 21, animals were euthanized and necropsied. Promising results were obtained regarding oxidative balance in groups G3 and G4. Both presented better PON1 activity in comparison with group G2 (P<0.05). Total leukocyte count of group G4 differed significantly from group G2 (P<0.05) on day 21. Myelogram values of animals from groups G3 and G4 were similar to those from G1; animals from G3 had lower numbers of promyelocytes and increased numbers of erythrocytes and rubriblasts than animals from G2 (P<0.05). In the present experimental study, aqueous wheat extract was safe at the doses used in the animals, and was an effective treatment for myelosuppression and for the prevention of an excessive release of free radicals induced by carboplatin." @default.
- W2891517346 created "2018-09-27" @default.
- W2891517346 creator A5016447202 @default.
- W2891517346 creator A5016551399 @default.
- W2891517346 creator A5023172420 @default.
- W2891517346 creator A5026801486 @default.
- W2891517346 creator A5028536966 @default.
- W2891517346 creator A5048852672 @default.
- W2891517346 creator A5053550864 @default.
- W2891517346 creator A5055508241 @default.
- W2891517346 creator A5091357174 @default.
- W2891517346 date "2018-09-13" @default.
- W2891517346 modified "2023-09-23" @default.
- W2891517346 title "Aqueous wheat extract (Triticuma estivum) prevents carboplatin-induced myelosuppression and oxidative stress in Wistar rats" @default.
- W2891517346 cites W1757407923 @default.
- W2891517346 cites W2007543485 @default.
- W2891517346 cites W2026260698 @default.
- W2891517346 cites W2040005390 @default.
- W2891517346 cites W2042806128 @default.
- W2891517346 cites W2060550391 @default.
- W2891517346 cites W20763325 @default.
- W2891517346 cites W2082010159 @default.
- W2891517346 cites W2113580640 @default.
- W2891517346 cites W2116645921 @default.
- W2891517346 cites W2121563202 @default.
- W2891517346 cites W2123250752 @default.
- W2891517346 cites W2146933403 @default.
- W2891517346 cites W2154085372 @default.
- W2891517346 cites W2760605823 @default.
- W2891517346 cites W2789988201 @default.
- W2891517346 doi "https://doi.org/10.1590/0103-8478cr20170810" @default.
- W2891517346 hasPublicationYear "2018" @default.
- W2891517346 type Work @default.
- W2891517346 sameAs 2891517346 @default.
- W2891517346 citedByCount "0" @default.
- W2891517346 crossrefType "journal-article" @default.
- W2891517346 hasAuthorship W2891517346A5016447202 @default.
- W2891517346 hasAuthorship W2891517346A5016551399 @default.
- W2891517346 hasAuthorship W2891517346A5023172420 @default.
- W2891517346 hasAuthorship W2891517346A5026801486 @default.
- W2891517346 hasAuthorship W2891517346A5028536966 @default.
- W2891517346 hasAuthorship W2891517346A5048852672 @default.
- W2891517346 hasAuthorship W2891517346A5053550864 @default.
- W2891517346 hasAuthorship W2891517346A5055508241 @default.
- W2891517346 hasAuthorship W2891517346A5091357174 @default.
- W2891517346 hasBestOaLocation W28915173461 @default.
- W2891517346 hasConcept C126322002 @default.
- W2891517346 hasConcept C140793950 @default.
- W2891517346 hasConcept C185592680 @default.
- W2891517346 hasConcept C2776151105 @default.
- W2891517346 hasConcept C2776694085 @default.
- W2891517346 hasConcept C2778239845 @default.
- W2891517346 hasConcept C2781451048 @default.
- W2891517346 hasConcept C2993907526 @default.
- W2891517346 hasConcept C556039675 @default.
- W2891517346 hasConcept C71924100 @default.
- W2891517346 hasConcept C86803240 @default.
- W2891517346 hasConcept C98274493 @default.
- W2891517346 hasConceptScore W2891517346C126322002 @default.
- W2891517346 hasConceptScore W2891517346C140793950 @default.
- W2891517346 hasConceptScore W2891517346C185592680 @default.
- W2891517346 hasConceptScore W2891517346C2776151105 @default.
- W2891517346 hasConceptScore W2891517346C2776694085 @default.
- W2891517346 hasConceptScore W2891517346C2778239845 @default.
- W2891517346 hasConceptScore W2891517346C2781451048 @default.
- W2891517346 hasConceptScore W2891517346C2993907526 @default.
- W2891517346 hasConceptScore W2891517346C556039675 @default.
- W2891517346 hasConceptScore W2891517346C71924100 @default.
- W2891517346 hasConceptScore W2891517346C86803240 @default.
- W2891517346 hasConceptScore W2891517346C98274493 @default.
- W2891517346 hasIssue "10" @default.
- W2891517346 hasLocation W28915173461 @default.
- W2891517346 hasLocation W28915173462 @default.
- W2891517346 hasLocation W28915173463 @default.
- W2891517346 hasOpenAccess W2891517346 @default.
- W2891517346 hasPrimaryLocation W28915173461 @default.
- W2891517346 hasRelatedWork W1972912540 @default.
- W2891517346 hasRelatedWork W2041291300 @default.
- W2891517346 hasRelatedWork W2062965163 @default.
- W2891517346 hasRelatedWork W2150125181 @default.
- W2891517346 hasRelatedWork W2350445292 @default.
- W2891517346 hasRelatedWork W2357464014 @default.
- W2891517346 hasRelatedWork W2748952813 @default.
- W2891517346 hasRelatedWork W2899084033 @default.
- W2891517346 hasRelatedWork W3016478976 @default.
- W2891517346 hasRelatedWork W2185009457 @default.
- W2891517346 hasVolume "48" @default.
- W2891517346 isParatext "false" @default.
- W2891517346 isRetracted "false" @default.
- W2891517346 magId "2891517346" @default.
- W2891517346 workType "article" @default.