FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891527834> ?p ?o ?g. }

• W2891527834 endingPage "968" @default.
• W2891527834 startingPage "968" @default.
• W2891527834 abstract "Cefaclor, a second-generation oral cephalosporin, is known to cause IgE-mediated hypersensitivity. Assays of serum-specific IgE (sIgE) to cefaclor are commercially available via the ImmunoCAP system (Thermo Fisher Scientific). While serum levels of sIgE >0.35 kU/L are considered indicative of an allergy, some patients with cefaclor allergy show low serum IgE levels. This study aimed to evaluate the proper cut-off levels of sIgE in the diagnosis of immediate hypersensitivity to cefaclor.A total of 269 patients with drug allergy history, who underwent assays of sIgE to cefaclor at Ajou University hospital and Dong-A University Hospital, were reviewed retrospectively. Among them, 193 patients exhibited cefaclor-induced immediate hypersensitivity with certain or probable causality of an adverse drug reaction according to the WHO-UMC (the World Health Organization-the Uppsala Monitoring Centre) algorithm, and 76 controls showed delayed hypersensitivity reactions to non-antibiotics.In total, 126 of the 193 patients (65.3%) experienced anaphylaxis; they had higher serum sIgE levels than patients with immediate hypersensitivity who did not experience anaphylaxis (6.36±12.39 kU/L vs. 4.28±13.61 kU/L, p<0.001). The best cut-off value for cefaclor-induced immediate hypersensitivity was 0.11 kU/L, with sensitivity of 80.2% and specificity of 81.6%. A cut-off value of 0.44 kU/L showed the best sensitivity (75.4%) and specificity (65.7%) for differentiating anaphylaxis from immediate hypersensitivity reactions.Patients with cefaclor anaphylaxis exhibit high serum IgE levels. A cut-off value of 0.11 kU/L of sIgE to cefaclor is proper for identifying patients with cefaclor allergy, and 0.44 kU/L may be useful to detect anaphylaxis." @default.
• W2891527834 created "2018-09-27" @default.
• W2891527834 creator A5005892142 @default.
• W2891527834 creator A5012280267 @default.
• W2891527834 creator A5038831454 @default.
• W2891527834 creator A5038852974 @default.
• W2891527834 creator A5044524626 @default.
• W2891527834 creator A5059572681 @default.
• W2891527834 creator A5064625853 @default.
• W2891527834 creator A5079628468 @default.
• W2891527834 creator A5091474946 @default.
• W2891527834 date "2018-01-01" @default.
• W2891527834 modified "2023-10-11" @default.
• W2891527834 title "Proper Cut-off Levels of Serum Specific IgE to Cefaclor for Patients with Cefaclor Allergy" @default.
• W2891527834 cites W1635988529 @default.
• W2891527834 cites W1964956727 @default.
• W2891527834 cites W1973214769 @default.
• W2891527834 cites W1974870112 @default.
• W2891527834 cites W1978474898 @default.
• W2891527834 cites W2005245159 @default.
• W2891527834 cites W2013487430 @default.
• W2891527834 cites W2058292096 @default.
• W2891527834 cites W2059554755 @default.
• W2891527834 cites W2073164009 @default.
• W2891527834 cites W2075032257 @default.
• W2891527834 cites W2075330346 @default.
• W2891527834 cites W2096606953 @default.
• W2891527834 cites W2120080661 @default.
• W2891527834 cites W2125885704 @default.
• W2891527834 cites W2126530318 @default.
• W2891527834 cites W2130733066 @default.
• W2891527834 cites W2185947623 @default.
• W2891527834 cites W2613180833 @default.
• W2891527834 cites W2753184214 @default.
• W2891527834 cites W4232794167 @default.
• W2891527834 doi "https://doi.org/10.3349/ymj.2018.59.8.968" @default.
• W2891527834 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6127431" @default.
• W2891527834 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30187704" @default.
• W2891527834 hasPublicationYear "2018" @default.
• W2891527834 type Work @default.
• W2891527834 sameAs 2891527834 @default.
• W2891527834 citedByCount "6" @default.
• W2891527834 countsByYear W28915278342019 @default.
• W2891527834 countsByYear W28915278342021 @default.
• W2891527834 countsByYear W28915278342022 @default.
• W2891527834 crossrefType "journal-article" @default.
• W2891527834 hasAuthorship W2891527834A5005892142 @default.
• W2891527834 hasAuthorship W2891527834A5012280267 @default.
• W2891527834 hasAuthorship W2891527834A5038831454 @default.
• W2891527834 hasAuthorship W2891527834A5038852974 @default.
• W2891527834 hasAuthorship W2891527834A5044524626 @default.
• W2891527834 hasAuthorship W2891527834A5059572681 @default.
• W2891527834 hasAuthorship W2891527834A5064625853 @default.
• W2891527834 hasAuthorship W2891527834A5079628468 @default.
• W2891527834 hasAuthorship W2891527834A5091474946 @default.
• W2891527834 hasBestOaLocation W28915278341 @default.
• W2891527834 hasConcept C126322002 @default.
• W2891527834 hasConcept C141105273 @default.
• W2891527834 hasConcept C159654299 @default.
• W2891527834 hasConcept C185592680 @default.
• W2891527834 hasConcept C203014093 @default.
• W2891527834 hasConcept C207480886 @default.
• W2891527834 hasConcept C2775933838 @default.
• W2891527834 hasConcept C2779060952 @default.
• W2891527834 hasConcept C2779766023 @default.
• W2891527834 hasConcept C2993280485 @default.
• W2891527834 hasConcept C501593827 @default.
• W2891527834 hasConcept C55493867 @default.
• W2891527834 hasConcept C64778159 @default.
• W2891527834 hasConcept C71924100 @default.
• W2891527834 hasConceptScore W2891527834C126322002 @default.
• W2891527834 hasConceptScore W2891527834C141105273 @default.
• W2891527834 hasConceptScore W2891527834C159654299 @default.
• W2891527834 hasConceptScore W2891527834C185592680 @default.
• W2891527834 hasConceptScore W2891527834C203014093 @default.
• W2891527834 hasConceptScore W2891527834C207480886 @default.
• W2891527834 hasConceptScore W2891527834C2775933838 @default.
• W2891527834 hasConceptScore W2891527834C2779060952 @default.
• W2891527834 hasConceptScore W2891527834C2779766023 @default.
• W2891527834 hasConceptScore W2891527834C2993280485 @default.
• W2891527834 hasConceptScore W2891527834C501593827 @default.
• W2891527834 hasConceptScore W2891527834C55493867 @default.
• W2891527834 hasConceptScore W2891527834C64778159 @default.
• W2891527834 hasConceptScore W2891527834C71924100 @default.
• W2891527834 hasFunder F4320322014 @default.
• W2891527834 hasFunder F4320322107 @default.
• W2891527834 hasIssue "8" @default.
• W2891527834 hasLocation W28915278341 @default.
• W2891527834 hasLocation W28915278342 @default.
• W2891527834 hasLocation W28915278343 @default.
• W2891527834 hasLocation W28915278344 @default.
• W2891527834 hasOpenAccess W2891527834 @default.
• W2891527834 hasPrimaryLocation W28915278341 @default.
• W2891527834 hasRelatedWork W1906382642 @default.
• W2891527834 hasRelatedWork W2092665604 @default.
• W2891527834 hasRelatedWork W2126074212 @default.
• W2891527834 hasRelatedWork W2126076031 @default.
• W2891527834 hasRelatedWork W2339256591 @default.

• next