Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891541616> ?p ?o ?g. }
- W2891541616 endingPage "86" @default.
- W2891541616 startingPage "81" @default.
- W2891541616 abstract "Purpose Epilepsy is considered a disorder of neural networks. Patients diagnosed with refractory epilepsy frequently experience attention impairments. Seizure activity in epilepsy may disturb brain networks and damage the brain function of attention. The aims of this study were to assess functional and causal connectivities of the attention networks and default mode network using resting-state functional magnetic resonance imaging (fMRI). Method Resting-state fMRI data were gathered from 19 patients with refractory epilepsy (mixed localization and aetiologies) and 21 healthy people. The fMRI data were analyzed by group independent component analysis (ICA) fMRI toolbox to extract dorsal attention network (DAN), ventral attention network (VAN), and default mode network (DMN). The components of the selected networks were compared between patients and healthy controls to explore the change in functional connectivity (FC). Granger causality analysis was performed by taking the aforementioned significant brain areas as regions of interest (ROIs) to calculate autoregression coefficients of each pair of ROIs. Comparisons were done to find the significantly different causal connectivity when FC was changed between patients and healthy controls. Results In DAN, the FC values of the bilateral frontal eye field (FEF) and left intraparietal sulcus (IPS) were decreased. In VAN, the FC values of the double-side ventral prefrontal cortex (vPFC) and the temporoparietal junction (TPJ) were reduced. As for DMN, the FC values of the bilateral medial prefrontal cortices (mPFC) were decreased whereas those for the bilateral precuneus (PCUN) were increased. Granger causal connectivity values were correlated: causal influence was decreased significantly from the left IPS (in DAN) to the double side of the vPFC but remained the same for the right FEF (in DAN) to the right TPJ. The value was decreased from the left PCUN (in DMN) to the right TPJ and FEF, and the causal flow from the right PCUN to the right TPJ and bilateral vPFC was also significantly inhibited (p < 0.05). Conclusion Frequent seizures in patients with refractory epilepsy may damage the cortex and disturb DAN, VAN, and DMN, leading to functional and causal connectivity alteration. In addition, epileptic activity may disrupt network interactions and further influence information communication." @default.
- W2891541616 created "2018-09-27" @default.
- W2891541616 creator A5022058318 @default.
- W2891541616 creator A5023273137 @default.
- W2891541616 creator A5027997590 @default.
- W2891541616 creator A5030446424 @default.
- W2891541616 creator A5034524285 @default.
- W2891541616 creator A5052957371 @default.
- W2891541616 creator A5061786742 @default.
- W2891541616 date "2018-11-01" @default.
- W2891541616 modified "2023-09-24" @default.
- W2891541616 title "Altered attention networks and DMN in refractory epilepsy: A resting-state functional and causal connectivity study" @default.
- W2891541616 cites W14177003 @default.
- W2891541616 cites W1514982086 @default.
- W2891541616 cites W1520390934 @default.
- W2891541616 cites W1560895878 @default.
- W2891541616 cites W1574914184 @default.
- W2891541616 cites W1604539019 @default.
- W2891541616 cites W1606616855 @default.
- W2891541616 cites W1760829075 @default.
- W2891541616 cites W1920696238 @default.
- W2891541616 cites W1965384329 @default.
- W2891541616 cites W1970224621 @default.
- W2891541616 cites W1971986290 @default.
- W2891541616 cites W1973880443 @default.
- W2891541616 cites W1985327120 @default.
- W2891541616 cites W1995932559 @default.
- W2891541616 cites W2003018758 @default.
- W2891541616 cites W2008123860 @default.
- W2891541616 cites W2019370496 @default.
- W2891541616 cites W2021287608 @default.
- W2891541616 cites W2025985542 @default.
- W2891541616 cites W2038068904 @default.
- W2891541616 cites W2039138222 @default.
- W2891541616 cites W2045758998 @default.
- W2891541616 cites W2050717100 @default.
- W2891541616 cites W2061564920 @default.
- W2891541616 cites W2063237661 @default.
- W2891541616 cites W2079450984 @default.
- W2891541616 cites W2080859877 @default.
- W2891541616 cites W2082207932 @default.
- W2891541616 cites W2083956595 @default.
- W2891541616 cites W2090664364 @default.
- W2891541616 cites W2098303658 @default.
- W2891541616 cites W2099478180 @default.
- W2891541616 cites W2101328227 @default.
- W2891541616 cites W2102691670 @default.
- W2891541616 cites W2106594083 @default.
- W2891541616 cites W2110169026 @default.
- W2891541616 cites W2121049815 @default.
- W2891541616 cites W2136435696 @default.
- W2891541616 cites W2151635492 @default.
- W2891541616 cites W2178225550 @default.
- W2891541616 cites W2332401200 @default.
- W2891541616 cites W2333662682 @default.
- W2891541616 cites W2508619212 @default.
- W2891541616 cites W2568034382 @default.
- W2891541616 cites W2687561162 @default.
- W2891541616 cites W2789988138 @default.
- W2891541616 cites W4295750005 @default.
- W2891541616 doi "https://doi.org/10.1016/j.yebeh.2018.06.045" @default.
- W2891541616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30243110" @default.
- W2891541616 hasPublicationYear "2018" @default.
- W2891541616 type Work @default.
- W2891541616 sameAs 2891541616 @default.
- W2891541616 citedByCount "28" @default.
- W2891541616 countsByYear W28915416162019 @default.
- W2891541616 countsByYear W28915416162020 @default.
- W2891541616 countsByYear W28915416162021 @default.
- W2891541616 countsByYear W28915416162022 @default.
- W2891541616 countsByYear W28915416162023 @default.
- W2891541616 crossrefType "journal-article" @default.
- W2891541616 hasAuthorship W2891541616A5022058318 @default.
- W2891541616 hasAuthorship W2891541616A5023273137 @default.
- W2891541616 hasAuthorship W2891541616A5027997590 @default.
- W2891541616 hasAuthorship W2891541616A5030446424 @default.
- W2891541616 hasAuthorship W2891541616A5034524285 @default.
- W2891541616 hasAuthorship W2891541616A5052957371 @default.
- W2891541616 hasAuthorship W2891541616A5061786742 @default.
- W2891541616 hasConcept C141516989 @default.
- W2891541616 hasConcept C15744967 @default.
- W2891541616 hasConcept C169760540 @default.
- W2891541616 hasConcept C169900460 @default.
- W2891541616 hasConcept C2778186239 @default.
- W2891541616 hasConcept C2778233910 @default.
- W2891541616 hasConcept C2779226451 @default.
- W2891541616 hasConcept C2781195155 @default.
- W2891541616 hasConcept C2781441883 @default.
- W2891541616 hasConcept C3018011982 @default.
- W2891541616 hasConcept C45715564 @default.
- W2891541616 hasConcept C47107517 @default.
- W2891541616 hasConcept C548259974 @default.
- W2891541616 hasConcept C66324658 @default.
- W2891541616 hasConcept C71924100 @default.
- W2891541616 hasConceptScore W2891541616C141516989 @default.
- W2891541616 hasConceptScore W2891541616C15744967 @default.
- W2891541616 hasConceptScore W2891541616C169760540 @default.
- W2891541616 hasConceptScore W2891541616C169900460 @default.