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• W2891558082 abstract "α-N-(Fmoc)Amino-γ-lactam dipeptides with a variety of β-substituents were synthesized stereoselectively with minimal β-elimination by routes employing, respectively, Mitsunobu chemistry and cyclic sulfamidate nucleophilic ring opening from trans- and cis-β-hydroxy-α-amino-γ-lactam precursors. This diversity-oriented method provides stereochemically pure dipeptide mimics bearing Cys, Ser, Thr, Dap, Dab, His, and other amino acid residues with constrained backbone and side chain conformations." @default.
• W2891558082 created "2018-09-27" @default.
• W2891558082 creator A5002942665 @default.
• W2891558082 creator A5021366295 @default.
• W2891558082 date "2018-09-19" @default.
• W2891558082 modified "2023-10-18" @default.
• W2891558082 title "Diversity-Oriented Syntheses of β-Substituted α-Amino γ-Lactam Peptide Mimics with Constrained Backbone and Side Chain Residues" @default.
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• W2891558082 doi "https://doi.org/10.1021/acs.orglett.8b02575" @default.
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