Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891574170> ?p ?o ?g. }
- W2891574170 abstract "Heterotopic ossification (HO) is the process of bone formation in tissues that are not usually osseous. It occurs in 60% of those with blast-related amputations. HO can result in reduced range of motion, pain, nerve impingement and can affect prosthesis fitting and is caused by a combination of mechanical, biological, local and systemic factors. As with normal bone formation and remodelling, it is expected that heterotopic bone responds to mechanical stimuli and understanding this relationship can give insight into the pathology. The objective of this research was to investigate whether a physiological 2D computational model that considers both mechanical and biological factors can be used to simulate HO in the residual limb of a trans-femoral amputee. The study found that characteristic morphologies of HO were reproduced by adjusting the loading environment. Significant effects were produced by changing the loading direction on the femur; this is potentially associated with different initial surgical interventions such as muscle myodesis. Also, initial treatment such as negative pressure through a dressing was found to change the shape of heterotopic bone." @default.
- W2891574170 created "2018-09-27" @default.
- W2891574170 creator A5056070707 @default.
- W2891574170 creator A5071279596 @default.
- W2891574170 date "2018-09-21" @default.
- W2891574170 modified "2023-09-29" @default.
- W2891574170 title "Application of a mechanobiological algorithm to investigate mechanical mediation of heterotopic bone in trans-femoral amputees" @default.
- W2891574170 cites W1813887555 @default.
- W2891574170 cites W1820921662 @default.
- W2891574170 cites W1854064841 @default.
- W2891574170 cites W1964963987 @default.
- W2891574170 cites W1965003995 @default.
- W2891574170 cites W1968493594 @default.
- W2891574170 cites W1970977697 @default.
- W2891574170 cites W1992837958 @default.
- W2891574170 cites W1998057512 @default.
- W2891574170 cites W2000138358 @default.
- W2891574170 cites W2004589506 @default.
- W2891574170 cites W2009823096 @default.
- W2891574170 cites W2013046278 @default.
- W2891574170 cites W2016748069 @default.
- W2891574170 cites W2017604695 @default.
- W2891574170 cites W2021551044 @default.
- W2891574170 cites W2022092514 @default.
- W2891574170 cites W2029899668 @default.
- W2891574170 cites W2032270391 @default.
- W2891574170 cites W2032516306 @default.
- W2891574170 cites W2041137495 @default.
- W2891574170 cites W2044611322 @default.
- W2891574170 cites W2055255429 @default.
- W2891574170 cites W2057464986 @default.
- W2891574170 cites W2059747051 @default.
- W2891574170 cites W2063356701 @default.
- W2891574170 cites W2067244504 @default.
- W2891574170 cites W2068862577 @default.
- W2891574170 cites W2074230216 @default.
- W2891574170 cites W2080068648 @default.
- W2891574170 cites W2080633310 @default.
- W2891574170 cites W2091447598 @default.
- W2891574170 cites W2105254921 @default.
- W2891574170 cites W2113679184 @default.
- W2891574170 cites W2113725410 @default.
- W2891574170 cites W2115754795 @default.
- W2891574170 cites W2118355184 @default.
- W2891574170 cites W2120389451 @default.
- W2891574170 cites W2123677555 @default.
- W2891574170 cites W2123700593 @default.
- W2891574170 cites W2129719137 @default.
- W2891574170 cites W2134086845 @default.
- W2891574170 cites W2136952503 @default.
- W2891574170 cites W2139484243 @default.
- W2891574170 cites W2142594416 @default.
- W2891574170 cites W2143690592 @default.
- W2891574170 cites W2145493145 @default.
- W2891574170 cites W2146112273 @default.
- W2891574170 cites W2147124927 @default.
- W2891574170 cites W2153057165 @default.
- W2891574170 cites W2154334945 @default.
- W2891574170 cites W2159103174 @default.
- W2891574170 cites W2159863517 @default.
- W2891574170 cites W2165489024 @default.
- W2891574170 cites W2171133614 @default.
- W2891574170 cites W2253909102 @default.
- W2891574170 cites W2294156923 @default.
- W2891574170 cites W2317019250 @default.
- W2891574170 cites W2336544185 @default.
- W2891574170 cites W2793944270 @default.
- W2891574170 cites W4237593632 @default.
- W2891574170 doi "https://doi.org/10.1038/s41598-018-32414-1" @default.
- W2891574170 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6155077" @default.
- W2891574170 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30242273" @default.
- W2891574170 hasPublicationYear "2018" @default.
- W2891574170 type Work @default.
- W2891574170 sameAs 2891574170 @default.
- W2891574170 citedByCount "2" @default.
- W2891574170 countsByYear W28915741702022 @default.
- W2891574170 crossrefType "journal-article" @default.
- W2891574170 hasAuthorship W2891574170A5056070707 @default.
- W2891574170 hasAuthorship W2891574170A5071279596 @default.
- W2891574170 hasBestOaLocation W28915741701 @default.
- W2891574170 hasConcept C105702510 @default.
- W2891574170 hasConcept C126322002 @default.
- W2891574170 hasConcept C136229726 @default.
- W2891574170 hasConcept C141071460 @default.
- W2891574170 hasConcept C170033053 @default.
- W2891574170 hasConcept C170700871 @default.
- W2891574170 hasConcept C192562407 @default.
- W2891574170 hasConcept C2778715743 @default.
- W2891574170 hasConcept C2780554211 @default.
- W2891574170 hasConcept C2780650075 @default.
- W2891574170 hasConcept C60465272 @default.
- W2891574170 hasConcept C71924100 @default.
- W2891574170 hasConceptScore W2891574170C105702510 @default.
- W2891574170 hasConceptScore W2891574170C126322002 @default.
- W2891574170 hasConceptScore W2891574170C136229726 @default.
- W2891574170 hasConceptScore W2891574170C141071460 @default.
- W2891574170 hasConceptScore W2891574170C170033053 @default.
- W2891574170 hasConceptScore W2891574170C170700871 @default.
- W2891574170 hasConceptScore W2891574170C192562407 @default.
- W2891574170 hasConceptScore W2891574170C2778715743 @default.