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- W2891634064 abstract "Current guideline recommendations for pharmacogenetic testing for clopidogrel by the American Heart Association/American College of Cardiology (AHA/ACC) contradict the Clinical Pharmacogenetics Implementation Consortium and the US FDA. The AHA/ACC recommends against routine pharmacogenetic testing for clopidogrel because no randomized controlled trials have demonstrated that testing improves patients' outcomes. However the AHA/ACC and the National Comprehensive Cancer Network (NCCN) recommend other pharmacogenetic tests in the absence of randomized controlled trials evidence. Using clopidogrel as a case example, we compared the evidence for other pharmacogenetic tests recommended by the AHA/ACC and NCCN. In patients that received percutaneous coronary intervention, the evidence supporting pharmacogenetic testing for clopidogrel is stronger than other pharmacogenetic tests recommended by the AHA/ACC and NCCN." @default.
- W2891634064 created "2018-09-27" @default.
- W2891634064 creator A5049741747 @default.
- W2891634064 creator A5052707649 @default.
- W2891634064 date "2018-10-01" @default.
- W2891634064 modified "2023-10-14" @default.
- W2891634064 title "Does cardiology hold pharmacogenetics to an inconsistent standard? A comparison of evidence among recommendations" @default.
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- W2891634064 doi "https://doi.org/10.2217/pgs-2018-0097" @default.
- W2891634064 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6219446" @default.
- W2891634064 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30196751" @default.
- W2891634064 hasPublicationYear "2018" @default.
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