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- W2891641168 abstract "Abstract Low levels of peripheral blood natural killer T ( NKT ) cells in cancer patients and a favorable outcome associated with a high number of tumor‐infiltrating NKT cells demonstrated in several studies indicated the important role of these immune cells in the antitumor response. With effective antitumor immunity via direct tumor lysis, cytokine modulation of effector cells and regulation of immunosuppressive cells, type I NKT cells display interesting features/properties for the rapidly developing chimeric antigen receptor ( CAR ) technology. Due to their restriction to the monomorphic HLA ‐like molecule CD 1d, but not to the polymorphic human leukocyte antigen ( HLA ), NKT CAR cells show potential for enabling autologous and allogeneic/off‐the‐shelf cancer immunotherapy. Promising results were obtained in preclinical NKT CAR cell studies, but clinical trials have not yet been conducted. In this review, we summarize the biological features of NKT cells, their role in antitumor immunity and recent advances in the development of NKT CAR cells." @default.
- W2891641168 created "2018-09-27" @default.
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- W2891641168 date "2018-10-09" @default.
- W2891641168 modified "2023-09-26" @default.
- W2891641168 title "NKT cells - New players in CAR cell immunotherapy?" @default.
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- W2891641168 cites W1607981534 @default.
- W2891641168 cites W1652153701 @default.
- W2891641168 cites W1659136311 @default.
- W2891641168 cites W1678468169 @default.
- W2891641168 cites W1871903510 @default.
- W2891641168 cites W1921796284 @default.
- W2891641168 cites W1942062746 @default.
- W2891641168 cites W1949861316 @default.
- W2891641168 cites W1963522404 @default.
- W2891641168 cites W1967455230 @default.
- W2891641168 cites W1969830803 @default.
- W2891641168 cites W1974917518 @default.
- W2891641168 cites W1981916745 @default.
- W2891641168 cites W1984847897 @default.
- W2891641168 cites W1989322067 @default.
- W2891641168 cites W1995515999 @default.
- W2891641168 cites W2016523043 @default.
- W2891641168 cites W2018809204 @default.
- W2891641168 cites W2020646453 @default.
- W2891641168 cites W2021202651 @default.
- W2891641168 cites W2023279370 @default.
- W2891641168 cites W2025141198 @default.
- W2891641168 cites W2025406167 @default.
- W2891641168 cites W2025671950 @default.
- W2891641168 cites W2026058426 @default.
- W2891641168 cites W2026555862 @default.
- W2891641168 cites W2027053879 @default.
- W2891641168 cites W2034769339 @default.
- W2891641168 cites W2044311205 @default.
- W2891641168 cites W2051549641 @default.
- W2891641168 cites W2056312413 @default.
- W2891641168 cites W2056315817 @default.
- W2891641168 cites W2058648826 @default.
- W2891641168 cites W2065363863 @default.
- W2891641168 cites W2087510980 @default.
- W2891641168 cites W2087654677 @default.
- W2891641168 cites W2089755940 @default.
- W2891641168 cites W2097790514 @default.
- W2891641168 cites W2100213157 @default.
- W2891641168 cites W2100495456 @default.
- W2891641168 cites W2101206430 @default.
- W2891641168 cites W2105557870 @default.
- W2891641168 cites W2113912833 @default.
- W2891641168 cites W2119695630 @default.
- W2891641168 cites W2120954350 @default.
- W2891641168 cites W2122029067 @default.
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- W2891641168 cites W2132835748 @default.
- W2891641168 cites W2134287140 @default.
- W2891641168 cites W2135054826 @default.
- W2891641168 cites W2136795220 @default.
- W2891641168 cites W2137181933 @default.
- W2891641168 cites W2144436556 @default.
- W2891641168 cites W2145794545 @default.
- W2891641168 cites W2145985838 @default.
- W2891641168 cites W2146227128 @default.
- W2891641168 cites W2152041843 @default.
- W2891641168 cites W2153416566 @default.
- W2891641168 cites W2153503008 @default.
- W2891641168 cites W2155738206 @default.
- W2891641168 cites W2161307276 @default.
- W2891641168 cites W2163270673 @default.
- W2891641168 cites W2165107917 @default.
- W2891641168 cites W2170316367 @default.
- W2891641168 cites W2179234980 @default.
- W2891641168 cites W2350813277 @default.
- W2891641168 cites W2398722604 @default.
- W2891641168 cites W2470318030 @default.
- W2891641168 cites W2505779381 @default.
- W2891641168 cites W2515679023 @default.
- W2891641168 cites W2529729107 @default.
- W2891641168 cites W2579192242 @default.
- W2891641168 cites W2588227649 @default.
- W2891641168 cites W2621650910 @default.
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- W2891641168 doi "https://doi.org/10.1111/ejh.13170" @default.
- W2891641168 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30187578" @default.
- W2891641168 hasPublicationYear "2018" @default.
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