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- W2891656573 abstract "Investigation of genetic susceptibility to cerebrovascular disease has been of growing interest. A systematic review of human studies assessing neurogenomic aspects of cerebrovascular disease was performed according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement. Any association study exploring genetic variants located in the exome associated with one of the major cerebrovascular diseases with at least 500 subjects was eligible for inclusion. Of 6874 manuscripts identified, 35 studies met the inclusion criteria. Most studies of interest focused on ischemic stroke and cerebrovascular occlusive disease. Large cohort genetic association studies on hemorrhagic cerebrovascular disease were less common. In addition to rare, well-established monogenic conditions with significant risk for cerebrovascular disease, a number of genetic variants are also relevant to cerebrovascular pathogenesis as part of a multifactorial process. The 45 polymorphisms identified were located in genes involved in processes related to endothelial and vascular health (15 (33.4%) variants), plasma lipid metabolism (10 (22.2%) variants), inflammation (9 (20%) variants), coagulation (3 (6.7%) variants), and blood pressure modulation (2 (4.4%) variants), and other (6 (13.3%) variants). This work represents a comprehensive overview of genetic variants in the exome relevant to ischemic and hemorrhagic stroke pathophysiology." @default.
- W2891656573 created "2018-09-27" @default.
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- W2891656573 date "2018-09-05" @default.
- W2891656573 modified "2023-10-16" @default.
- W2891656573 title "Genetic susceptibility to cerebrovascular disease: A systematic review" @default.
- W2891656573 cites W1192849952 @default.
- W2891656573 cites W1827856311 @default.
- W2891656573 cites W1912907434 @default.
- W2891656573 cites W1969990934 @default.
- W2891656573 cites W1972969071 @default.
- W2891656573 cites W1981832507 @default.
- W2891656573 cites W1985759654 @default.
- W2891656573 cites W1992016465 @default.
- W2891656573 cites W1996281895 @default.
- W2891656573 cites W1996938145 @default.
- W2891656573 cites W1997338841 @default.
- W2891656573 cites W2004840822 @default.
- W2891656573 cites W2005368543 @default.
- W2891656573 cites W2014941181 @default.
- W2891656573 cites W2015007646 @default.
- W2891656573 cites W2015191281 @default.
- W2891656573 cites W2025173319 @default.
- W2891656573 cites W2030121961 @default.
- W2891656573 cites W2035204504 @default.
- W2891656573 cites W2043564997 @default.
- W2891656573 cites W2049691341 @default.
- W2891656573 cites W2051024032 @default.
- W2891656573 cites W2053076905 @default.
- W2891656573 cites W2057045896 @default.
- W2891656573 cites W2060427373 @default.
- W2891656573 cites W2061173128 @default.
- W2891656573 cites W2066413604 @default.
- W2891656573 cites W2067287561 @default.
- W2891656573 cites W2078382344 @default.
- W2891656573 cites W2081227651 @default.
- W2891656573 cites W2082955001 @default.
- W2891656573 cites W2090211293 @default.
- W2891656573 cites W2091026283 @default.
- W2891656573 cites W2091583677 @default.
- W2891656573 cites W2092769781 @default.
- W2891656573 cites W2099593831 @default.
- W2891656573 cites W2107752760 @default.
- W2891656573 cites W2108162914 @default.
- W2891656573 cites W2108527532 @default.
- W2891656573 cites W2108601334 @default.
- W2891656573 cites W2114306699 @default.
- W2891656573 cites W2114533404 @default.
- W2891656573 cites W2126989192 @default.
- W2891656573 cites W2132998463 @default.
- W2891656573 cites W2135455133 @default.
- W2891656573 cites W2142076534 @default.
- W2891656573 cites W2146190354 @default.
- W2891656573 cites W2146701013 @default.
- W2891656573 cites W2156051913 @default.
- W2891656573 cites W2157304020 @default.
- W2891656573 cites W2157622195 @default.
- W2891656573 cites W2163215334 @default.
- W2891656573 cites W2163331125 @default.
- W2891656573 cites W2165715420 @default.
- W2891656573 cites W2167604858 @default.
- W2891656573 cites W2198069207 @default.
- W2891656573 cites W2206501848 @default.
- W2891656573 cites W2215127032 @default.
- W2891656573 cites W2233504250 @default.
- W2891656573 cites W2235639808 @default.
- W2891656573 cites W2237172764 @default.
- W2891656573 cites W2258546476 @default.
- W2891656573 cites W2264761307 @default.
- W2891656573 cites W2265621338 @default.
- W2891656573 cites W2286668281 @default.
- W2891656573 cites W2297531970 @default.
- W2891656573 cites W2306783063 @default.
- W2891656573 cites W2312872563 @default.
- W2891656573 cites W2335251894 @default.
- W2891656573 cites W2412641479 @default.
- W2891656573 cites W2417960221 @default.
- W2891656573 cites W2497971182 @default.
- W2891656573 cites W2510836520 @default.
- W2891656573 cites W2527660462 @default.
- W2891656573 cites W2550865537 @default.
- W2891656573 cites W2555410361 @default.
- W2891656573 cites W2560161082 @default.
- W2891656573 cites W2563021430 @default.
- W2891656573 cites W2564640632 @default.