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- W2891658811 abstract "Abstract Periodontitis is a complex chronic inflammatory noncommunicable disease, initiated by the development of a dysbiotic microbial plaque biofilm below the gingival margin. Whilst the pathogenic biofilm is a “necessary cause” of periodontitis, it is insufficient on its own to cause the disease, and a destructive immune‐inflammatory response is a key to the translation of risk to destructive events. Other exposures or “component causes” include individual genetic predisposition, lifestyle (including smoking and nutrition), and environmental factors. Dietary nutrients are essential for life as they provide crucial energy sources in the form of macronutrients, as well as important cofactors in the form of micronutrients, which regulate the functionality of enzymes during the regulation of anabolic and catabolic processes in human cells. Moreover, micronutrients can regulate gene transcription factors, such as the proinflammatory nuclear factor kappa B and the anti‐inflammatory nuclear factor (erythroid‐derived 2)‐like 2. This review focuses on the role of vitamins (vitamin A, carotenoids, the vitamin B complex, vitamins C, D, and E, and coenzyme Q10) and minerals (calcium, magnesium, iron, zinc, potassium, copper, manganese, and selenium) in human physiology and the impact of their deficiencies upon periodontal health and disease." @default.
- W2891658811 created "2018-09-27" @default.
- W2891658811 creator A5002276380 @default.
- W2891658811 creator A5010763767 @default.
- W2891658811 creator A5051000545 @default.
- W2891658811 creator A5059982821 @default.
- W2891658811 creator A5086328223 @default.
- W2891658811 date "2018-09-09" @default.
- W2891658811 modified "2023-10-09" @default.
- W2891658811 title "Effect of micronutrient malnutrition on periodontal disease and periodontal therapy" @default.
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