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- W2891660573 abstract "Malignant peritoneal mesothelioma (MPM) is a rare disease whose natural history is confined to the peritoneal space. Systemic chemotherapy has little impact on survival of patients with MPM. A surgical procedure with a goal of resection of all visible evidence of disease, called cytoreductive surgery (CRS) has been utilized in MPM patients. Also, regional chemotherapy with hyperthermic intraperitoneal chemotherapy (HIPEC) and normothermic intraperitoneal chemotherapy long-term (NIPEC-LT) have been effectively utilized in MPM patients. In the absence of CRS and HIPEC the median survival of MPM patients is approximately 1 year. The aggressive surgical approach plus regional chemotherapy has increased the median survival to more than 5 years. With NIPEC-LT added on, 70% 5-year survival has been reported. Knowledgeable patient selection for treatment is mandatory. The use of CRS, HIPEC and NIPEC-LT has greatly benefited patients with MPM. Global application of these treatments is indicated." @default.
- W2891660573 created "2018-09-27" @default.
- W2891660573 creator A5043918821 @default.
- W2891660573 date "2018-10-01" @default.
- W2891660573 modified "2023-10-05" @default.
- W2891660573 title "Update on the management of malignant peritoneal mesothelioma" @default.
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- W2891660573 doi "https://doi.org/10.21037/tlcr.2018.08.03" @default.
- W2891660573 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6204413" @default.
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