Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891664976> ?p ?o ?g. }
- W2891664976 endingPage "129" @default.
- W2891664976 startingPage "121" @default.
- W2891664976 abstract "Peptidoglycan is the key component forming the backbone of bacterial cell wall. It can be recognized by a group of pattern recognition receptors, known as peptidoglycan recognition proteins (PGRPs) in insects and higher animals. PGRPs may serve as immune receptors or N-acetylmuramoyl-L-alanine amidases (EC 3.5.1.28). Here, we report the characterization of a short PGRP, PGRP-S1, from the oriental armyworm, Mythimna separata. MsePGRP-S1 cDNA encodes a protein of 197 amino acids (aa) with a PGRP domain of about 150 aa. MsePGRP-S1 was expressed in several tissues of naïve larvae, including hemocytes, midgut, fat body and epidermis. Bacterial challenges caused variable changes in different tissues at the mRNA level. The recombinant protein bound strongly to Staphylococcus aureus and purified peptidoglycans from Staphylococcus aureus and Bacillus subtilis. It can inhibit the growth of gram-negative and gram-positive bacteria by disrupting bacterial surface. It can degrade peptidoglycans from Escherichia coli and Staphylococcus aureus. Taken together, these data demonstrate that M. separata PGRP-S1 is involved in defending against bacteria." @default.
- W2891664976 created "2018-09-27" @default.
- W2891664976 creator A5003377806 @default.
- W2891664976 creator A5022817604 @default.
- W2891664976 creator A5034071007 @default.
- W2891664976 creator A5037605902 @default.
- W2891664976 creator A5045492403 @default.
- W2891664976 creator A5054504686 @default.
- W2891664976 creator A5090744085 @default.
- W2891664976 date "2019-01-01" @default.
- W2891664976 modified "2023-09-29" @default.
- W2891664976 title "Characterization of PGRP-S1 from the oriental armyworm, Mythimna separata" @default.
- W2891664976 cites W1593657963 @default.
- W2891664976 cites W1971116536 @default.
- W2891664976 cites W1980927664 @default.
- W2891664976 cites W1985241441 @default.
- W2891664976 cites W1986496696 @default.
- W2891664976 cites W1994599007 @default.
- W2891664976 cites W1995649215 @default.
- W2891664976 cites W1999839839 @default.
- W2891664976 cites W2000530029 @default.
- W2891664976 cites W2000667679 @default.
- W2891664976 cites W2003810642 @default.
- W2891664976 cites W2006768051 @default.
- W2891664976 cites W2014512239 @default.
- W2891664976 cites W2015160750 @default.
- W2891664976 cites W2016143376 @default.
- W2891664976 cites W2029845836 @default.
- W2891664976 cites W2035903989 @default.
- W2891664976 cites W2036755790 @default.
- W2891664976 cites W2037134815 @default.
- W2891664976 cites W2042539249 @default.
- W2891664976 cites W2042824737 @default.
- W2891664976 cites W2046656994 @default.
- W2891664976 cites W2047549277 @default.
- W2891664976 cites W2050242801 @default.
- W2891664976 cites W2052129538 @default.
- W2891664976 cites W2052779789 @default.
- W2891664976 cites W2064082040 @default.
- W2891664976 cites W2066785573 @default.
- W2891664976 cites W2071063810 @default.
- W2891664976 cites W2074898833 @default.
- W2891664976 cites W2075570572 @default.
- W2891664976 cites W2080359892 @default.
- W2891664976 cites W2092259900 @default.
- W2891664976 cites W2101949291 @default.
- W2891664976 cites W2113474003 @default.
- W2891664976 cites W2136986799 @default.
- W2891664976 cites W2149861263 @default.
- W2891664976 cites W2151655863 @default.
- W2891664976 cites W2152207030 @default.
- W2891664976 cites W2153379129 @default.
- W2891664976 cites W2162394246 @default.
- W2891664976 cites W2264988334 @default.
- W2891664976 cites W2303551394 @default.
- W2891664976 cites W2551901296 @default.
- W2891664976 cites W2735668408 @default.
- W2891664976 cites W2767032889 @default.
- W2891664976 cites W2770645308 @default.
- W2891664976 cites W2775743738 @default.
- W2891664976 cites W2785470816 @default.
- W2891664976 cites W2794182586 @default.
- W2891664976 cites W2809478061 @default.
- W2891664976 cites W4252700310 @default.
- W2891664976 doi "https://doi.org/10.1016/j.dci.2018.09.009" @default.
- W2891664976 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30227217" @default.
- W2891664976 hasPublicationYear "2019" @default.
- W2891664976 type Work @default.
- W2891664976 sameAs 2891664976 @default.
- W2891664976 citedByCount "10" @default.
- W2891664976 countsByYear W28916649762021 @default.
- W2891664976 countsByYear W28916649762022 @default.
- W2891664976 countsByYear W28916649762023 @default.
- W2891664976 crossrefType "journal-article" @default.
- W2891664976 hasAuthorship W2891664976A5003377806 @default.
- W2891664976 hasAuthorship W2891664976A5022817604 @default.
- W2891664976 hasAuthorship W2891664976A5034071007 @default.
- W2891664976 hasAuthorship W2891664976A5037605902 @default.
- W2891664976 hasAuthorship W2891664976A5045492403 @default.
- W2891664976 hasAuthorship W2891664976A5054504686 @default.
- W2891664976 hasAuthorship W2891664976A5090744085 @default.
- W2891664976 hasConcept C104317684 @default.
- W2891664976 hasConcept C111289621 @default.
- W2891664976 hasConcept C125235067 @default.
- W2891664976 hasConcept C136449434 @default.
- W2891664976 hasConcept C170493617 @default.
- W2891664976 hasConcept C177756618 @default.
- W2891664976 hasConcept C18903297 @default.
- W2891664976 hasConcept C19655278 @default.
- W2891664976 hasConcept C2776634448 @default.
- W2891664976 hasConcept C2777272437 @default.
- W2891664976 hasConcept C2779489039 @default.
- W2891664976 hasConcept C2779518903 @default.
- W2891664976 hasConcept C2779578577 @default.
- W2891664976 hasConcept C4937899 @default.
- W2891664976 hasConcept C523546767 @default.
- W2891664976 hasConcept C54355233 @default.
- W2891664976 hasConcept C547475151 @default.