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- W2891670534 abstract "Introduction Despite the tendency for rural individuals with advanced heart failure (HF) to experience poor outcomes compared to urban counterparts, little is known about how rurality may impact survival and time to transplant for recipients of left ventricular assist devices (LVAD). Rural LVAD recipients will experience decreased survival time and increased time to transplant in the first year following device implantation when compared to urban counterparts. Methods This study was a secondary analysis of LVAD data from a Midwestern academic medical center maintained by INTERMACS. Subjects were designated as rural or urban using county level data from the 2010 U.S. Census. Descriptive statistics and frequencies were calculated. Kaplan-Meier curves and Cox proportional hazards models were used to compare hazards, survival time, and time to transplant in rural and urban subjects. Results The sample included 182 LVAD recipients implanted from June 2010 to July 2016. The majority were married, Caucasian, males (71%) with a high school education. Nineteen subjects (10.4%) died in the first year post-implantation. Of these 19 subjects, 42.1% lived in rural counties and 57.9% lived in urban counties. Mean survival time was 169 (±115) days. Forty-eight subjects (26.4%) were transplanted; 43.8% were rural and 56.2% were urban. Mean time to transplant was 183 (±85) days. Kaplan-Meier curves ( Figures 1 and 2 ) and Cox proportional hazard models were not significant. (Survival: HR .87, .35-2.16, p=0.76; Transplant: HR .91, .52-1.62, p=0.75). Conclusions Although previous reports indicated disparate outcomes in rural individuals with advanced HF, this data supports comparable survival time and time to transplant for rural and urban LVAD recipients. Future investigations to confirm these findings in other implanting centers and explore the impact of rurality on other important outcomes such as adverse event frequency, hospitalizations and patient-reported quality of life are necessary." @default.
- W2891670534 created "2018-09-27" @default.
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- W2891670534 date "2018-08-01" @default.
- W2891670534 modified "2023-09-26" @default.
- W2891670534 title "Rural LVAD Recipients Experience Similar Survival and Transplant Times Compared to Urban Counterparts" @default.
- W2891670534 doi "https://doi.org/10.1016/j.cardfail.2018.07.421" @default.
- W2891670534 hasPublicationYear "2018" @default.
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