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- W2891675246 abstract "ABSTRACT Noninvasive neurostimulation plays a pivotal role in direct control of neural circuit and modulating neuronal function. However, it is difficult to balance both spatial focality and depth of penetration in stimulating deep neurons. Here, we designed time-division, frequency & polarity modulation synthesis (TMFPMS) for stimulating deep neurons noninvasively with low-frequency envelope. We demonstrated its spatial resolution: mm-level via computational simulation including finite element analysis and Hodgkin-Huxley action potential model. Taken together, the results of this study indicate that TMFPMS neurostimulation with high spatial resolution is steerable and may replace traditional implanted electrode." @default.
- W2891675246 created "2018-09-27" @default.
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- W2891675246 date "2018-09-14" @default.
- W2891675246 modified "2023-09-27" @default.
- W2891675246 title "Multiple modulation synthesis with high spatial resolution for noninvasive deep neurostimulation" @default.
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- W2891675246 doi "https://doi.org/10.1101/416057" @default.
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