FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891679303> ?p ?o ?g. }

• W2891679303 abstract "ABSTRACT Executive function develops rapidly during adolescence, and failures of executive function are associated with both risk-taking behaviors and psychopathology. However, it remains relatively unknown how structural brain networks mature during this critical period to facilitate energetically demanding transitions to activate the frontoparietal system, which is critical for executive function. In a sample of 946 human youths (ages 8-23 yr) who completed diffusion imaging as part of the Philadelphia Neurodevelopment Cohort, we capitalized upon recent advances in network control theory in order to calculate the control energy necessary to activate the frontoparietal system given the existing structural network topology. We found that the control energy required to activate the frontoparietal system declined with development. Moreover, we found that this control energy pattern contains sufficient information to make accurate predictions about individuals’ brain maturity. Finally, the control energy costs of the cingulate cortex were negatively correlated with executive performance, and partially mediated the development of executive performance with age. These results could not be explained by changes in general network control properties or in network modularity. Taken together, our results reveal a mechanism by which structural networks develop during adolescence to facilitate the instantiation of activation states necessary for executive function. SIGNIFICANCE STATEMENT Executive function undergoes protracted development during youth, but it is unknown how structural brain networks mature to facilitate the activation of the frontoparietal cortex that is critical for executive processes. Here, we leverage recent advances in network control theory to establish that structural brain networks evolve in adolescence to lower the energetic cost of activating the frontoparietal system. Our results suggest a new mechanistic framework for understanding how brain network maturation supports cognition, with clear implications for disorders marked by executive dysfunction, such as ADHD and psychosis." @default.
• W2891679303 created "2018-09-27" @default.
• W2891679303 creator A5000246497 @default.
• W2891679303 creator A5009266404 @default.
• W2891679303 creator A5018607314 @default.
• W2891679303 creator A5021061052 @default.
• W2891679303 creator A5024589723 @default.
• W2891679303 creator A5033736827 @default.
• W2891679303 creator A5034999945 @default.
• W2891679303 creator A5037974362 @default.
• W2891679303 creator A5039906500 @default.
• W2891679303 creator A5041082600 @default.
• W2891679303 creator A5043997958 @default.
• W2891679303 creator A5044323141 @default.
• W2891679303 creator A5049920415 @default.
• W2891679303 creator A5052952633 @default.
• W2891679303 creator A5053568428 @default.
• W2891679303 creator A5058169245 @default.
• W2891679303 creator A5058433895 @default.
• W2891679303 creator A5060417820 @default.
• W2891679303 creator A5087180664 @default.
• W2891679303 date "2018-09-23" @default.
• W2891679303 modified "2023-10-14" @default.
• W2891679303 title "Optimization of Energy State Transition Trajectory Supports the Development of Executive Function During Youth" @default.
• W2891679303 cites W1685870920 @default.
• W2891679303 cites W1924326075 @default.
• W2891679303 cites W1965092590 @default.
• W2891679303 cites W1969129137 @default.
• W2891679303 cites W1975148201 @default.
• W2891679303 cites W1985168009 @default.
• W2891679303 cites W1996954170 @default.
• W2891679303 cites W1997538961 @default.
• W2891679303 cites W2000133863 @default.
• W2891679303 cites W2002807356 @default.
• W2891679303 cites W2004758461 @default.
• W2891679303 cites W2005900392 @default.
• W2891679303 cites W2006096283 @default.
• W2891679303 cites W2009499611 @default.
• W2891679303 cites W2014506049 @default.
• W2891679303 cites W2019930104 @default.
• W2891679303 cites W2020044743 @default.
• W2891679303 cites W2042505987 @default.
• W2891679303 cites W2050141897 @default.
• W2891679303 cites W2062718236 @default.
• W2891679303 cites W2063404606 @default.
• W2891679303 cites W2069088601 @default.
• W2891679303 cites W2069724292 @default.
• W2891679303 cites W2074617510 @default.
• W2891679303 cites W2075893253 @default.
• W2891679303 cites W2082848122 @default.
• W2891679303 cites W2100145912 @default.
• W2891679303 cites W2101135654 @default.
• W2891679303 cites W2106131177 @default.
• W2891679303 cites W2122609459 @default.
• W2891679303 cites W2127309075 @default.
• W2891679303 cites W2131181615 @default.
• W2891679303 cites W2142059961 @default.
• W2891679303 cites W2146278257 @default.
• W2891679303 cites W2166109328 @default.
• W2891679303 cites W2167822639 @default.
• W2891679303 cites W2168844688 @default.
• W2891679303 cites W2169683381 @default.
• W2891679303 cites W2211147350 @default.
• W2891679303 cites W2257984621 @default.
• W2891679303 cites W2301669941 @default.
• W2891679303 cites W2472295098 @default.
• W2891679303 cites W2514959782 @default.
• W2891679303 cites W2573891029 @default.
• W2891679303 cites W2593696428 @default.
• W2891679303 cites W2753939719 @default.
• W2891679303 cites W2759098134 @default.
• W2891679303 cites W2759856034 @default.
• W2891679303 cites W2766650025 @default.
• W2891679303 cites W2774446342 @default.
• W2891679303 cites W2782149223 @default.
• W2891679303 cites W2790978796 @default.
• W2891679303 cites W2806887831 @default.
• W2891679303 cites W2807683509 @default.
• W2891679303 cites W2833620410 @default.
• W2891679303 cites W2963186114 @default.
• W2891679303 cites W2971739325 @default.
• W2891679303 cites W2977883299 @default.
• W2891679303 cites W3103071805 @default.
• W2891679303 cites W3104445344 @default.
• W2891679303 cites W3106209931 @default.
• W2891679303 cites W4241074797 @default.
• W2891679303 cites W4245509354 @default.
• W2891679303 cites W4255455317 @default.
• W2891679303 cites W4295750005 @default.
• W2891679303 doi "https://doi.org/10.1101/424929" @default.
• W2891679303 hasPublicationYear "2018" @default.
• W2891679303 type Work @default.
• W2891679303 sameAs 2891679303 @default.
• W2891679303 citedByCount "3" @default.
• W2891679303 countsByYear W28916793032019 @default.
• W2891679303 countsByYear W28916793032020 @default.
• W2891679303 crossrefType "posted-content" @default.
• W2891679303 hasAuthorship W2891679303A5000246497 @default.
• W2891679303 hasAuthorship W2891679303A5009266404 @default.
• W2891679303 hasAuthorship W2891679303A5018607314 @default.

• next