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- W2891694132 abstract "The aim of this study was to estimate the comparative safety of initiating commonly used opioids among older, long-stay United States nursing home residents with fracture hospitalizations. We conducted a new-user retrospective cohort study of nursing home residents initiating short-acting oxycodone, hydrocodone, or tramadol by merging the 2011–2013 Minimum Data Set 3.0 to Medicare hospitalization and pharmacy claims. Residents (≥ 65 years, no cancer or hospice use) contributed treatment episodes (> 120 days with no prior opioid claims) and were followed for 180 days until incident fracture hospitalization (hip, femur, humerus, pelvis, radius/ulna), death (competing risk), treatment changes (e.g., discontinuation), or administrative censoring. Competing risks models with inverse probability of treatment weighting were used to estimate subdistribution hazard ratios (HRSD) and 95% confidence intervals (CI). Overall, 110,862 residents contributed 134,432 treatment episodes: 14,373 oxycodone; 69,182 hydrocodone; and 50,877 tramadol initiators. The incidences of fracture hospitalizations per 100 person-years were 9.4 (95% CI 7.5–11.7) for oxycodone, 7.9 (95% CI 7.1–8.8) for hydrocodone, and 5.0 (95% CI 4.3–5.7) for tramadol initiators. In weighted models, oxycodone initiators had a similar rate of fractures to hydrocodone initiators (HRSD 1.08, 95% CI 0.79–1.48). Tramadol initiators had lower fracture rates than hydrocodone initiators (HRSD 0.67, 95% CI 0.56–0.80). The lower rate of fractures that we documented among tramadol initiators compared with hydrocodone initiators is consistent, albeit attenuated compared with prior studies among community-dwelling older adults. However, overall fracture rates were lower than in community settings, potentially due to the limited risk of falling in this population with limited mobility." @default.
- W2891694132 created "2018-09-27" @default.
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- W2891694132 date "2018-09-06" @default.
- W2891694132 modified "2023-10-11" @default.
- W2891694132 title "Commonly Initiated Opioids and Risk of Fracture Hospitalizations in United States Nursing Homes" @default.
- W2891694132 cites W1605248640 @default.
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- W2891694132 cites W1849521086 @default.
- W2891694132 cites W1965999023 @default.
- W2891694132 cites W1973885323 @default.
- W2891694132 cites W1978738190 @default.
- W2891694132 cites W1980766464 @default.
- W2891694132 cites W1981789809 @default.
- W2891694132 cites W1998165842 @default.
- W2891694132 cites W2008417518 @default.
- W2891694132 cites W2013089513 @default.
- W2891694132 cites W2013288507 @default.
- W2891694132 cites W2032183686 @default.
- W2891694132 cites W2042397700 @default.
- W2891694132 cites W2051514672 @default.
- W2891694132 cites W2052957337 @default.
- W2891694132 cites W2053440173 @default.
- W2891694132 cites W2058790826 @default.
- W2891694132 cites W2062189312 @default.
- W2891694132 cites W2065167866 @default.
- W2891694132 cites W2068813660 @default.
- W2891694132 cites W2088027173 @default.
- W2891694132 cites W2092466879 @default.
- W2891694132 cites W2103971455 @default.
- W2891694132 cites W2107981536 @default.
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- W2891694132 cites W2110818436 @default.
- W2891694132 cites W2111208438 @default.
- W2891694132 cites W2113651274 @default.
- W2891694132 cites W2115364368 @default.
- W2891694132 cites W2117084822 @default.
- W2891694132 cites W2118732431 @default.
- W2891694132 cites W2120177388 @default.
- W2891694132 cites W2123778879 @default.
- W2891694132 cites W2140074098 @default.
- W2891694132 cites W2142495742 @default.
- W2891694132 cites W2145579475 @default.
- W2891694132 cites W2148395959 @default.
- W2891694132 cites W2150288991 @default.
- W2891694132 cites W2150291618 @default.
- W2891694132 cites W2150885850 @default.
- W2891694132 cites W2154746519 @default.
- W2891694132 cites W2158753674 @default.
- W2891694132 cites W2164275915 @default.
- W2891694132 cites W2164595809 @default.
- W2891694132 cites W2166196858 @default.
- W2891694132 cites W2166293995 @default.
- W2891694132 cites W2168897356 @default.
- W2891694132 cites W2169544550 @default.
- W2891694132 cites W2296986887 @default.
- W2891694132 cites W2301043062 @default.
- W2891694132 cites W2429408914 @default.
- W2891694132 cites W2495724511 @default.
- W2891694132 cites W2504347855 @default.
- W2891694132 cites W2513845892 @default.
- W2891694132 cites W2568896786 @default.
- W2891694132 cites W2604288947 @default.
- W2891694132 cites W2735259895 @default.
- W2891694132 cites W2735301415 @default.
- W2891694132 cites W2752022710 @default.
- W2891694132 cites W2759065094 @default.
- W2891694132 cites W2759440056 @default.
- W2891694132 cites W2772513731 @default.
- W2891694132 cites W2777515402 @default.
- W2891694132 cites W2784168825 @default.
- W2891694132 cites W2805769053 @default.
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- W2891694132 cites W2964012073 @default.
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- W2891694132 doi "https://doi.org/10.1007/s40266-018-0583-x" @default.
- W2891694132 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6785836" @default.
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- W2891694132 hasPublicationYear "2018" @default.
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