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- W2891695199 abstract "The drug discovery process entails the comparison and evaluation of various drug candidates before lead selection for advancement into later stages of preclinical and clinical development. Appropriate analysis of tumor growth data at the preclinical stage will aid in effective interpretation of the preclinical studies. In general, tumor growth models have a degree of intrinsic variability, so studies must be powered with an adequate number of replicates to enable differentiation of the anticipated effects. Interpretation of the findings and implications for translation to human disease, obtained from preclinical models, is rarely straightforward and limited by various factors. This chapter outlines various quantitative approaches commonly used to assess antitumor activity in preclinical models." @default.
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- W2891695199 date "2018-01-01" @default.
- W2891695199 modified "2023-09-26" @default.
- W2891695199 title "Evaluation of Tumor Growth Inhibition in Preclinical Tumor Models: A Quantitative Approach" @default.
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- W2891695199 doi "https://doi.org/10.1007/978-981-13-0496-5_8" @default.
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