FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891706028> ?p ?o ?g. }

• W2891706028 endingPage "1415" @default.
• W2891706028 startingPage "1405" @default.
• W2891706028 abstract "The ubiquitous bacterial second messenger bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) is involved in the regulation of numerous processes including biofilm formation, motility, virulence, cell cycle and differentiation. In this study, we searched the genome of the ecologically important marine alphaproteobacterium Dinoroseobacter shibae DFL12T for genes encoding putative c-di-GMP-modulating enzymes. Overall, D. shibae was found to possess two diguanylate cyclases (Dshi_2814 and Dshi_2820) as well as two c-di-GMP-specific phosphodiesterases (Dhi_0329 and Dshi_3065). Recombinant expression and purification followed by enzymatic analysis revealed that all four proteins exhibit their proposed activity. Furthermore, adjacent to Dshi_2814 we identified a gene encoding a heme nitric oxide/oxygen binding (H-NOX) protein. These proteins are often found in association with c-di-GMP signal transduction pathways and modulate their function through binding of diatomic gases such as nitric oxide. Here, we demonstrate that H-NOX constitutes a functional unit together with the diguanylate cyclase Dshi_2814. NO-bound H-NOX strongly inhibits DGC activity. Based on these results, and with respect to previously published data including micro-array analysis, we propose an interlinkage of c-di-GMP signalling with cell–cell communication and differentiation in D. shibae." @default.
• W2891706028 created "2018-09-27" @default.
• W2891706028 creator A5004160673 @default.
• W2891706028 creator A5010690959 @default.
• W2891706028 creator A5015675537 @default.
• W2891706028 creator A5048732015 @default.
• W2891706028 creator A5089038231 @default.
• W2891706028 date "2018-11-01" @default.
• W2891706028 modified "2023-09-26" @default.
• W2891706028 title "Nitric oxide controls c-di-GMP turnover in Dinoroseobacter shibae" @default.
• W2891706028 cites W1558274313 @default.
• W2891706028 cites W1873199501 @default.
• W2891706028 cites W1976347829 @default.
• W2891706028 cites W1987637706 @default.
• W2891706028 cites W1993476352 @default.
• W2891706028 cites W2003481405 @default.
• W2891706028 cites W2004938907 @default.
• W2891706028 cites W2005986251 @default.
• W2891706028 cites W2010116808 @default.
• W2891706028 cites W2010466313 @default.
• W2891706028 cites W2028622989 @default.
• W2891706028 cites W2034091457 @default.
• W2891706028 cites W2036331323 @default.
• W2891706028 cites W2046539688 @default.
• W2891706028 cites W2058660100 @default.
• W2891706028 cites W2061314216 @default.
• W2891706028 cites W2065065108 @default.
• W2891706028 cites W2077537471 @default.
• W2891706028 cites W2077685605 @default.
• W2891706028 cites W2078149894 @default.
• W2891706028 cites W2081634057 @default.
• W2891706028 cites W2086323657 @default.
• W2891706028 cites W2093832152 @default.
• W2891706028 cites W2098883074 @default.
• W2891706028 cites W2100837269 @default.
• W2891706028 cites W2113557404 @default.
• W2891706028 cites W2114196916 @default.
• W2891706028 cites W2132665880 @default.
• W2891706028 cites W2146444149 @default.
• W2891706028 cites W2160765784 @default.
• W2891706028 cites W2165420858 @default.
• W2891706028 cites W2605157159 @default.
• W2891706028 cites W2608718733 @default.
• W2891706028 doi "https://doi.org/10.1099/mic.0.000714" @default.
• W2891706028 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30222100" @default.
• W2891706028 hasPublicationYear "2018" @default.
• W2891706028 type Work @default.
• W2891706028 sameAs 2891706028 @default.
• W2891706028 citedByCount "6" @default.
• W2891706028 countsByYear W28917060282019 @default.
• W2891706028 countsByYear W28917060282020 @default.
• W2891706028 countsByYear W28917060282022 @default.
• W2891706028 countsByYear W28917060282023 @default.
• W2891706028 crossrefType "journal-article" @default.
• W2891706028 hasAuthorship W2891706028A5004160673 @default.
• W2891706028 hasAuthorship W2891706028A5010690959 @default.
• W2891706028 hasAuthorship W2891706028A5015675537 @default.
• W2891706028 hasAuthorship W2891706028A5048732015 @default.
• W2891706028 hasAuthorship W2891706028A5089038231 @default.
• W2891706028 hasBestOaLocation W28917060281 @default.
• W2891706028 hasConcept C134018914 @default.
• W2891706028 hasConcept C181199279 @default.
• W2891706028 hasConcept C185592680 @default.
• W2891706028 hasConcept C2777622882 @default.
• W2891706028 hasConcept C519581460 @default.
• W2891706028 hasConcept C55493867 @default.
• W2891706028 hasConcept C62478195 @default.
• W2891706028 hasConcept C86803240 @default.
• W2891706028 hasConcept C91415057 @default.
• W2891706028 hasConcept C95444343 @default.
• W2891706028 hasConceptScore W2891706028C134018914 @default.
• W2891706028 hasConceptScore W2891706028C181199279 @default.
• W2891706028 hasConceptScore W2891706028C185592680 @default.
• W2891706028 hasConceptScore W2891706028C2777622882 @default.
• W2891706028 hasConceptScore W2891706028C519581460 @default.
• W2891706028 hasConceptScore W2891706028C55493867 @default.
• W2891706028 hasConceptScore W2891706028C62478195 @default.
• W2891706028 hasConceptScore W2891706028C86803240 @default.
• W2891706028 hasConceptScore W2891706028C91415057 @default.
• W2891706028 hasConceptScore W2891706028C95444343 @default.
• W2891706028 hasIssue "11" @default.
• W2891706028 hasLocation W28917060281 @default.
• W2891706028 hasLocation W28917060282 @default.
• W2891706028 hasOpenAccess W2891706028 @default.
• W2891706028 hasPrimaryLocation W28917060281 @default.
• W2891706028 hasRelatedWork W1970659243 @default.
• W2891706028 hasRelatedWork W1993093413 @default.
• W2891706028 hasRelatedWork W2076325817 @default.
• W2891706028 hasRelatedWork W2090249917 @default.
• W2891706028 hasRelatedWork W2388905353 @default.
• W2891706028 hasRelatedWork W2509976068 @default.
• W2891706028 hasRelatedWork W3096728664 @default.
• W2891706028 hasRelatedWork W3128616355 @default.
• W2891706028 hasRelatedWork W72147876 @default.
• W2891706028 hasRelatedWork W2183738312 @default.
• W2891706028 hasVolume "164" @default.
• W2891706028 isParatext "false" @default.
• W2891706028 isRetracted "false" @default.

• next