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- W2891712574 endingPage "48" @default.
- W2891712574 startingPage "37" @default.
- W2891712574 abstract "Phagocytes are cells of the immune system that play important roles in phagocytosis, respiratory burst and degranulation-key components of innate immunity and response to infection. This diverse group of cells includes monocytes, macrophages, dendritic cells, neutrophils, eosinophils, and basophils-heterogeneous cell populations possessing cell and tissue-specific functions of which cellular metabolism comprises a critical underpinning. Core functions of phagocytic cells are diverse and sensitive to alterations in environmental- and tissue-specific nutrients and growth factors. As phagocytic cells adapt to these extracellular cues, cellular processes are altered and may contribute to pathogenesis. The considerable degree of functional heterogeneity among monocyte, neutrophil, and other phagocytic cell populations necessitates diverse metabolism. As we review our current understanding of metabolism in phagocytic cells, gaps are focused on to highlight the need for additional studies that hopefully enable improved cell-based strategies for counteracting cancer and other diseases." @default.
- W2891712574 created "2018-09-27" @default.
- W2891712574 creator A5004928669 @default.
- W2891712574 creator A5068577073 @default.
- W2891712574 creator A5076604315 @default.
- W2891712574 creator A5086290367 @default.
- W2891712574 date "2018-09-14" @default.
- W2891712574 modified "2023-10-17" @default.
- W2891712574 title "Diversity and environmental adaptation of phagocytic cell metabolism" @default.
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