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- W2891714842 abstract "The present study was designed to further investigate the C21 steroidal glycosides in Cynanchum plants. Two new steroidal glycosides based on a 13, 14:14, 15-disecopregnane-type aglycone, komaroside P (1) and komaroside Q (2), together with three known compounds (3-5) were isolated from the whole herbs of Cynanchum komarovii. The aglycones of compounds 1 and 2 were two new disecopregnane. Their structures were elucidated on the basis of 1D, 2D NMR spectroscopic data and acid hydrolysis. All the compounds (1-5) showed potent inhibitory activities against human leukemia cell lines (HL-60) with IC50 values ranging from 16.6 to 26.3 μmol·L-1, compared to the positive control 5-fluorouracil (6.4 μmol·L-1)." @default.
- W2891714842 created "2018-09-27" @default.
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- W2891714842 date "2018-08-01" @default.
- W2891714842 modified "2023-09-29" @default.
- W2891714842 title "Two new C21 steroidal glycosides isolated from Cynanchum komarovii" @default.
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- W2891714842 doi "https://doi.org/10.1016/s1875-5364(18)30098-0" @default.
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