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• W2891738014 abstract "This study examined the impacts of Macondo oil from the Deepwater Horizon oil spill, both alone and in conjunction with exposure to the known fish pathogen Vibrio anguillarum, on the expression of five immune-related gene transcripts of red snapper (il8, il10, tnfa, il1b, and igm). In order to elucidate this impact, six different test conditions were used: one Control group (No oil/No pathogen), one Low oil/No pathogen group (tPAH50 = 0.563 μg/L), one High oil/No pathogen group (tPAH50 = 17.084 μg/L, one No oil/Pathogen group, one Low oil/Pathogen group (tPAH50 = 0.736 μg/L), and one High oil/Pathogen group (tPAH50 = 15.799 μg/L). Fish were exposed to their respective oil concentrations for one week. On day 7 of the experiment, all fish were placed into new tanks (with or without V. anguillarum) for one hour. At three time points (day 8, day 10, and day 17), fish organs were harvested and placed into RNAlater, and qPCR was run for examination of the above specific immune genes as well as cyp1a1. Our results suggest that cyp1a1 transcripts were upregulated in oil-exposed groups throughout the experiment, confirming oil exposure, and that all five immune gene transcripts were upregulated on day 8, but were generally downregulated or showed no differences from controls on days 10 and 17. Finally, both oil and pathogen exposure had impacts on growth." @default.
• W2891738014 created "2018-09-27" @default.
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• W2891738014 date "2018-11-01" @default.
• W2891738014 modified "2023-09-26" @default.
• W2891738014 title "Deepwater Horizon oil alone and in conjunction with Vibrio anguillarum exposure modulates immune response and growth in red snapper (Lutjanus campechanus)" @default.
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• W2891738014 doi "https://doi.org/10.1016/j.aquatox.2018.09.002" @default.
• W2891738014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30223188" @default.
• W2891738014 hasPublicationYear "2018" @default.
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