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- W2891755109 abstract "Breast cancer continues to be a leading cause of mortality among women. While at an early stage, localized breast cancer is easily treated; however, advanced stages of disease continue to carry a high mortality rate. The discrepancy in treatment success highlights that current treatments are insufficient to treat advanced-stage breast cancer. As new and improved treatments have been sought, one therapeutic approach has gained considerable attention. Oncolytic viruses are uniquely capable of targeting cancer cells through intrinsic or engineered means. They come in many forms, mainly from four major virus groups as defined by the Baltimore classification system. These vectors can target and kill cancer cells, and even stimulate immunotherapeutic effects in patients. This review discusses not only individual oncolytic viruses pursued in the context of breast cancer treatment but also the emergence of combination therapies with current or new therapies, which has become a particularly promising strategy for treatment of breast cancer. Overall, oncolytic virotherapy is a promising strategy for increased treatment efficacy for advanced breast cancer and consequently provides a unique platform for personalized treatments in patients." @default.
- W2891755109 created "2018-09-27" @default.
- W2891755109 creator A5035435017 @default.
- W2891755109 creator A5080578519 @default.
- W2891755109 date "2018-10-04" @default.
- W2891755109 modified "2023-10-18" @default.
- W2891755109 title "Oncolytic Virotherapy for Breast Cancer Treatment" @default.
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- W2891755109 doi "https://doi.org/10.2174/1566523218666180910163805" @default.
- W2891755109 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7499349" @default.
- W2891755109 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30207220" @default.
- W2891755109 hasPublicationYear "2018" @default.
- W2891755109 type Work @default.