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- W2891777229 abstract "Abstract Water soluble fluorescent graphene nanodots (GND) have been successfully prepared through a bottom up approach from brominated pyrene via alkaline hydrothermal condensation. FT‐IR, UV‐Vis, Raman, XRD, AFM, and TEM studies have shown the formation of −OH group rich nanodots having graphene features with an approximate size of 90 nm. Steady state and 3D fluorescence studies have shown efficient fluorescence emission with maximum at 540 nm upon excitation at 450 nm in pH≤7. Plasmid deoxyribonucleic acid (plasmid DNA) and bovine serum albumin (BSA) have shown their interaction with GND, which was studied via fluorescence quenching of GND and BSA, respectively. Selective quenching of the Förster resonance energy transfer (FRET) of BSA‐GND conjugate via ascorbic acid (AA) has been used to construct a calibration curve for AA estimation with a linear range and limit of detection of 34.00–112.00 μ mole/L and 31.343 μ mole/L, respectively. GND has also shown concentration‐dependent turn off chemosensing towards heavy metals like Pb 2+ , Cu 2+ , Hg 2+ and Zn 2+ . In‐vitro multicolor fluorescence imaging has been observed in GND‐labelled HeLa (human cervical cancer) and NIH‐3T3 (mouse embryonic fibroblast) cell lines with better uptake by HeLa cells. GND also has shown very high viability for both the cell lines up to the tested concentration of 300 μ g/mL." @default.
- W2891777229 created "2018-09-27" @default.
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- W2891777229 date "2018-09-03" @default.
- W2891777229 modified "2023-09-30" @default.
- W2891777229 title "Water Soluble Fluorescent Graphene Nanodots" @default.
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- W2891777229 doi "https://doi.org/10.1002/cnma.201800285" @default.
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