FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891796817> ?p ?o ?g. }

• W2891796817 abstract "Early acute periprosthetic joint infections (PJIs) treated with debridement, antibiotics and implant retention (DAIR) have failure rates ranging from 10% to 60%. We determined the efficacy of applying local gentamicin-impregnated beads and/or sponges during debridement in early PJI.Patients with early acute PJI, defined as less than 21 days of symptoms and treated with DAIR within 90 days after index surgery, were retrospectively evaluated. Early failure was defined as PJI-related death, the need for implant removal or a second DAIR or antibiotic suppressive therapy owing to persistent signs of infection, all within 60 days after initial debridement. Overall failure was defined as implant removal at any timepoint during follow-up. A 1:1 propensity score matching was performed to correct for confounding factors.A total of 386 patients were included. Local gentamicin was applied in 293 patients (75.9%) and was withheld in 93 patients (24.1%). Multivariate analysis demonstrated that the use of local gentamicin was independently associated with early failure (OR = 1.97, 95% CI = 1.12-3.48). After propensity matching, early failure was 40.3% in the gentamicin group versus 26.0% in the control group (P = 0.06) and overall failure was 5.2% in the gentamicin group versus 2.6% in the control group (P = 0.40). These numbers remained when solely analysing the application of gentamicin-impregnated sponges.Even after propensity score matching, failure rates remained higher if local gentamicin-impregnated beads and/or sponges were administered in early acute PJI. Based on these results, their use should be discouraged." @default.
• W2891796817 created "2018-09-27" @default.
• W2891796817 creator A5000695416 @default.
• W2891796817 creator A5004811626 @default.
• W2891796817 creator A5030033036 @default.
• W2891796817 creator A5036572424 @default.
• W2891796817 creator A5042622789 @default.
• W2891796817 creator A5048008292 @default.
• W2891796817 creator A5052819243 @default.
• W2891796817 creator A5055461951 @default.
• W2891796817 creator A5087129912 @default.
• W2891796817 date "2018-09-05" @default.
• W2891796817 modified "2023-09-26" @default.
• W2891796817 title "Use of gentamicin-impregnated beads or sponges in the treatment of early acute periprosthetic joint infection: a propensity score analysis" @default.
• W2891796817 cites W1618139394 @default.
• W2891796817 cites W1622127150 @default.
• W2891796817 cites W1909802012 @default.
• W2891796817 cites W1914001895 @default.
• W2891796817 cites W1955254598 @default.
• W2891796817 cites W1956309777 @default.
• W2891796817 cites W2011103472 @default.
• W2891796817 cites W2013896921 @default.
• W2891796817 cites W2016632197 @default.
• W2891796817 cites W2018581754 @default.
• W2891796817 cites W2023394860 @default.
• W2891796817 cites W2030967154 @default.
• W2891796817 cites W2052786983 @default.
• W2891796817 cites W2058347132 @default.
• W2891796817 cites W2069966578 @default.
• W2891796817 cites W2077518515 @default.
• W2891796817 cites W2083173530 @default.
• W2891796817 cites W2087343736 @default.
• W2891796817 cites W2091764958 @default.
• W2891796817 cites W2094719731 @default.
• W2891796817 cites W2095839952 @default.
• W2891796817 cites W2108058261 @default.
• W2891796817 cites W2108152814 @default.
• W2891796817 cites W2111057193 @default.
• W2891796817 cites W2119106297 @default.
• W2891796817 cites W2121051550 @default.
• W2891796817 cites W2168598616 @default.
• W2891796817 cites W2264600275 @default.
• W2891796817 cites W2291618503 @default.
• W2891796817 cites W2292247928 @default.
• W2891796817 cites W2294778003 @default.
• W2891796817 cites W2430390307 @default.
• W2891796817 cites W2548871791 @default.
• W2891796817 cites W2598976535 @default.
• W2891796817 cites W2765336172 @default.
• W2891796817 cites W2765793315 @default.
• W2891796817 cites W2768619442 @default.
• W2891796817 cites W2795195063 @default.
• W2891796817 doi "https://doi.org/10.1093/jac/dky354" @default.
• W2891796817 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30189006" @default.
• W2891796817 hasPublicationYear "2018" @default.
• W2891796817 type Work @default.
• W2891796817 sameAs 2891796817 @default.
• W2891796817 citedByCount "4" @default.
• W2891796817 countsByYear W28917968172019 @default.
• W2891796817 countsByYear W28917968172021 @default.
• W2891796817 countsByYear W28917968172022 @default.
• W2891796817 countsByYear W28917968172023 @default.
• W2891796817 crossrefType "journal-article" @default.
• W2891796817 hasAuthorship W2891796817A5000695416 @default.
• W2891796817 hasAuthorship W2891796817A5004811626 @default.
• W2891796817 hasAuthorship W2891796817A5030033036 @default.
• W2891796817 hasAuthorship W2891796817A5036572424 @default.
• W2891796817 hasAuthorship W2891796817A5042622789 @default.
• W2891796817 hasAuthorship W2891796817A5048008292 @default.
• W2891796817 hasAuthorship W2891796817A5052819243 @default.
• W2891796817 hasAuthorship W2891796817A5055461951 @default.
• W2891796817 hasAuthorship W2891796817A5087129912 @default.
• W2891796817 hasBestOaLocation W28917968171 @default.
• W2891796817 hasConcept C126322002 @default.
• W2891796817 hasConcept C141071460 @default.
• W2891796817 hasConcept C17923572 @default.
• W2891796817 hasConcept C2775832221 @default.
• W2891796817 hasConcept C2777438270 @default.
• W2891796817 hasConcept C2777787772 @default.
• W2891796817 hasConcept C2778120723 @default.
• W2891796817 hasConcept C2778336525 @default.
• W2891796817 hasConcept C2781411149 @default.
• W2891796817 hasConcept C501593827 @default.
• W2891796817 hasConcept C71924100 @default.
• W2891796817 hasConcept C77350462 @default.
• W2891796817 hasConcept C86803240 @default.
• W2891796817 hasConcept C89423630 @default.
• W2891796817 hasConceptScore W2891796817C126322002 @default.
• W2891796817 hasConceptScore W2891796817C141071460 @default.
• W2891796817 hasConceptScore W2891796817C17923572 @default.
• W2891796817 hasConceptScore W2891796817C2775832221 @default.
• W2891796817 hasConceptScore W2891796817C2777438270 @default.
• W2891796817 hasConceptScore W2891796817C2777787772 @default.
• W2891796817 hasConceptScore W2891796817C2778120723 @default.
• W2891796817 hasConceptScore W2891796817C2778336525 @default.
• W2891796817 hasConceptScore W2891796817C2781411149 @default.
• W2891796817 hasConceptScore W2891796817C501593827 @default.
• W2891796817 hasConceptScore W2891796817C71924100 @default.
• W2891796817 hasConceptScore W2891796817C77350462 @default.
• W2891796817 hasConceptScore W2891796817C86803240 @default.

• next