Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891812761> ?p ?o ?g. }
- W2891812761 abstract "Although the major role of Nrf2 has long been established as a transcription factor for providing cellular protection against oxidative stress, multiple pieces of research and reviews now claim exactly the opposite. The dilemma - “to activate or inhibit” the protein requires an immediate answer, which evidently links cellular metabolism to the causes and purpose of cancer. Profusely growing cancerous cells have prolific energy requirements, which can only be fulfilled by modulating cellular metabolism. This review highlights the cause and effect of Nrf2 modulation in cancer that in turn channelize cellular metabolism, thereby fulfilling the energy requirements of cancer cells. The present work also highlights the purpose of genetic mutations in Nrf2, in relation to cellular metabolism in cancer cells, thus pointing out a newer approach where parallel mutations may be the key factor to decide whether to activate or inhibit Nrf2." @default.
- W2891812761 created "2018-09-27" @default.
- W2891812761 creator A5029953730 @default.
- W2891812761 creator A5040566091 @default.
- W2891812761 creator A5051873619 @default.
- W2891812761 creator A5064329694 @default.
- W2891812761 creator A5080076598 @default.
- W2891812761 date "2020-07-15" @default.
- W2891812761 modified "2023-10-17" @default.
- W2891812761 title "Cancer Cell Metabolism Featuring Nrf2" @default.
- W2891812761 cites W1275502776 @default.
- W2891812761 cites W1672445637 @default.
- W2891812761 cites W1789875395 @default.
- W2891812761 cites W1850426716 @default.
- W2891812761 cites W1898716493 @default.
- W2891812761 cites W1969461041 @default.
- W2891812761 cites W1972779889 @default.
- W2891812761 cites W1973103230 @default.
- W2891812761 cites W1976949137 @default.
- W2891812761 cites W1981636483 @default.
- W2891812761 cites W1986688031 @default.
- W2891812761 cites W1988593777 @default.
- W2891812761 cites W1991631628 @default.
- W2891812761 cites W1992724001 @default.
- W2891812761 cites W1995675594 @default.
- W2891812761 cites W2005828644 @default.
- W2891812761 cites W2010720331 @default.
- W2891812761 cites W2014349355 @default.
- W2891812761 cites W2015243552 @default.
- W2891812761 cites W2025341515 @default.
- W2891812761 cites W2028991058 @default.
- W2891812761 cites W2040827479 @default.
- W2891812761 cites W2048548143 @default.
- W2891812761 cites W2050720471 @default.
- W2891812761 cites W2050739474 @default.
- W2891812761 cites W2053047691 @default.
- W2891812761 cites W2057228368 @default.
- W2891812761 cites W2057721542 @default.
- W2891812761 cites W2078245176 @default.
- W2891812761 cites W2080601555 @default.
- W2891812761 cites W2089035516 @default.
- W2891812761 cites W2092152920 @default.
- W2891812761 cites W2092323527 @default.
- W2891812761 cites W2095860292 @default.
- W2891812761 cites W2102322990 @default.
- W2891812761 cites W2104718696 @default.
- W2891812761 cites W2116516144 @default.
- W2891812761 cites W2117594441 @default.
- W2891812761 cites W2117692326 @default.
- W2891812761 cites W2121053107 @default.
- W2891812761 cites W2125719936 @default.
- W2891812761 cites W2129726289 @default.
- W2891812761 cites W2136706193 @default.
- W2891812761 cites W2139126860 @default.
- W2891812761 cites W2143373379 @default.
- W2891812761 cites W2146558971 @default.
- W2891812761 cites W2147924866 @default.
- W2891812761 cites W2153178365 @default.
- W2891812761 cites W2163471981 @default.
- W2891812761 cites W2167803469 @default.
- W2891812761 cites W2168395641 @default.
- W2891812761 cites W2169516568 @default.
- W2891812761 cites W2213679004 @default.
- W2891812761 cites W2313491323 @default.
- W2891812761 cites W2325787544 @default.
- W2891812761 cites W2327305889 @default.
- W2891812761 cites W2333137319 @default.
- W2891812761 cites W2336310263 @default.
- W2891812761 cites W2417535489 @default.
- W2891812761 cites W2419860237 @default.
- W2891812761 cites W2515118862 @default.
- W2891812761 cites W2536311229 @default.
- W2891812761 cites W2576501240 @default.
- W2891812761 cites W2587567491 @default.
- W2891812761 cites W2604444973 @default.
- W2891812761 cites W2604612121 @default.
- W2891812761 cites W2620411088 @default.
- W2891812761 cites W2745891591 @default.
- W2891812761 cites W2801988573 @default.
- W2891812761 cites W4237937003 @default.
- W2891812761 doi "https://doi.org/10.2174/1570163815666180911092443" @default.
- W2891812761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30207221" @default.
- W2891812761 hasPublicationYear "2020" @default.
- W2891812761 type Work @default.
- W2891812761 sameAs 2891812761 @default.
- W2891812761 citedByCount "1" @default.
- W2891812761 crossrefType "journal-article" @default.
- W2891812761 hasAuthorship W2891812761A5029953730 @default.
- W2891812761 hasAuthorship W2891812761A5040566091 @default.
- W2891812761 hasAuthorship W2891812761A5051873619 @default.
- W2891812761 hasAuthorship W2891812761A5064329694 @default.
- W2891812761 hasAuthorship W2891812761A5080076598 @default.
- W2891812761 hasConcept C104317684 @default.
- W2891812761 hasConcept C121608353 @default.
- W2891812761 hasConcept C134018914 @default.
- W2891812761 hasConcept C1491633281 @default.
- W2891812761 hasConcept C2776151105 @default.
- W2891812761 hasConcept C2986317502 @default.
- W2891812761 hasConcept C2991704936 @default.
- W2891812761 hasConcept C2994198108 @default.