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• W2891817481 abstract "The DNA loop extrusion model is a provocative new concept explaining the formation of chromatin loops that revolutionizes understanding of genome organization. Central to this model is the structural maintenance of chromosomes (SMC) protein family, which is now thought to function as a DNA motor. In this Perspective, we review and reinterpret the current knowledge of SMC structure and function and propose a novel mechanism for SMC motor activity. Nichols and Corces summarize the current knowledge of SMC structure and function and propose a new mechanism for SMC motor activity, which is central to the DNA loop extrusion model of genome organization." @default.
• W2891817481 created "2018-09-27" @default.
• W2891817481 creator A5005061316 @default.
• W2891817481 creator A5082436986 @default.
• W2891817481 date "2018-09-24" @default.
• W2891817481 modified "2023-10-11" @default.
• W2891817481 title "A tethered-inchworm model of SMC DNA translocation" @default.
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• W2891817481 doi "https://doi.org/10.1038/s41594-018-0135-4" @default.
• W2891817481 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6311135" @default.
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• W2891817481 hasPublicationYear "2018" @default.
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