FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891825862> ?p ?o ?g. }

• W2891825862 endingPage "243" @default.
• W2891825862 startingPage "236" @default.
• W2891825862 abstract "The cerulein-induced mouse pancreatitis model is a well-established, commonly used representation of human chronic pancreatitis pathology. Although studies report sex-dependent differences in human chronic pancreatitis, there are no studies in this model directly comparing sex response to pancreatic injury and recovery. Therefore, we designed a study to investigate whether sex- dependent differences in chronic pancreatitis injury and recovery exist in the cerulein-induced pancreatitis model.Adult male and female C57BL/6 mice were administered cerulein (50 μg/kg, 5 hourly intraperitoneal injections/day, 3 days/week) for 4 weeks to induce chronic pancreatitis; control mice received normal saline injections. Pancreata and blood were harvested at 4 days (as injury group) or 4 weeks (as recovery group) after the last injection. Amylase secretion was measured from the serum. Acinar injury was scored on H&E sections. Fibrosis was assessed by Sirius Red and collagen immunofluorescence staining.Compared to time-matched controls, injury group displayed decreased body and pancreas weight, and increased acinar injury and fibrosis, with no significant differences between males and females. Recovery group demonstrated recovery of body weight, partial recovery of pancreas weight, reversal of acinar injury, and partial reversal of fibrosis, with no significant differences between males and females. Amylase secretion/body weight was similar across all groups.Male and female mice of the cerulein-induced chronic pancreatitis demonstrate similar responses to chronic pancreatitis injury and recovery. Although this model may not sufficiently emulate sex-dependent responses in human chronic pancreatitis, our study supports that both sexes of mice from this model can be used for the study of chronic pancreatitis." @default.
• W2891825862 created "2018-09-27" @default.
• W2891825862 creator A5012677271 @default.
• W2891825862 creator A5015697902 @default.
• W2891825862 creator A5027490283 @default.
• W2891825862 creator A5028189969 @default.
• W2891825862 creator A5028293886 @default.
• W2891825862 creator A5030872984 @default.
• W2891825862 creator A5037465115 @default.
• W2891825862 creator A5060060979 @default.
• W2891825862 creator A5079266060 @default.
• W2891825862 creator A5081834953 @default.
• W2891825862 creator A5090405049 @default.
• W2891825862 date "2018-09-01" @default.
• W2891825862 modified "2023-09-27" @default.
• W2891825862 title "Comparable Responses in Male and Female Mice to Cerulein-Induced Chronic Pancreatic Injury and Recovery." @default.
• W2891825862 cites W1579488798 @default.
• W2891825862 cites W177021851 @default.
• W2891825862 cites W1963777718 @default.
• W2891825862 cites W1977379410 @default.
• W2891825862 cites W1981281003 @default.
• W2891825862 cites W1984218525 @default.
• W2891825862 cites W1990814447 @default.
• W2891825862 cites W1992289635 @default.
• W2891825862 cites W1995745717 @default.
• W2891825862 cites W2001496794 @default.
• W2891825862 cites W2011361286 @default.
• W2891825862 cites W2012442346 @default.
• W2891825862 cites W2016221014 @default.
• W2891825862 cites W2037923169 @default.
• W2891825862 cites W2045567984 @default.
• W2891825862 cites W2046076113 @default.
• W2891825862 cites W2059221926 @default.
• W2891825862 cites W2064172690 @default.
• W2891825862 cites W2072943291 @default.
• W2891825862 cites W2073149519 @default.
• W2891825862 cites W2080963091 @default.
• W2891825862 cites W2083449603 @default.
• W2891825862 cites W2096677890 @default.
• W2891825862 cites W2102506028 @default.
• W2891825862 cites W2107669818 @default.
• W2891825862 cites W2136056948 @default.
• W2891825862 cites W2137192368 @default.
• W2891825862 cites W2143057135 @default.
• W2891825862 cites W2143790225 @default.
• W2891825862 cites W2150286564 @default.
• W2891825862 cites W2150403843 @default.
• W2891825862 cites W2155773128 @default.
• W2891825862 cites W2161296120 @default.
• W2891825862 cites W2193115587 @default.
• W2891825862 cites W2465936260 @default.
• W2891825862 cites W2512420944 @default.
• W2891825862 cites W2515840034 @default.
• W2891825862 cites W2594634338 @default.
• W2891825862 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6327960" @default.
• W2891825862 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30636940" @default.
• W2891825862 hasPublicationYear "2018" @default.
• W2891825862 type Work @default.
• W2891825862 sameAs 2891825862 @default.
• W2891825862 citedByCount "1" @default.
• W2891825862 countsByYear W28918258622023 @default.
• W2891825862 crossrefType "journal-article" @default.
• W2891825862 hasAuthorship W2891825862A5012677271 @default.
• W2891825862 hasAuthorship W2891825862A5015697902 @default.
• W2891825862 hasAuthorship W2891825862A5027490283 @default.
• W2891825862 hasAuthorship W2891825862A5028189969 @default.
• W2891825862 hasAuthorship W2891825862A5028293886 @default.
• W2891825862 hasAuthorship W2891825862A5030872984 @default.
• W2891825862 hasAuthorship W2891825862A5037465115 @default.
• W2891825862 hasAuthorship W2891825862A5060060979 @default.
• W2891825862 hasAuthorship W2891825862A5079266060 @default.
• W2891825862 hasAuthorship W2891825862A5081834953 @default.
• W2891825862 hasAuthorship W2891825862A5090405049 @default.
• W2891825862 hasConcept C126322002 @default.
• W2891825862 hasConcept C134018914 @default.
• W2891825862 hasConcept C2775967933 @default.
• W2891825862 hasConcept C2777397205 @default.
• W2891825862 hasConcept C2778764654 @default.
• W2891825862 hasConcept C2780471426 @default.
• W2891825862 hasConcept C2780559512 @default.
• W2891825862 hasConcept C71924100 @default.
• W2891825862 hasConceptScore W2891825862C126322002 @default.
• W2891825862 hasConceptScore W2891825862C134018914 @default.
• W2891825862 hasConceptScore W2891825862C2775967933 @default.
• W2891825862 hasConceptScore W2891825862C2777397205 @default.
• W2891825862 hasConceptScore W2891825862C2778764654 @default.
• W2891825862 hasConceptScore W2891825862C2780471426 @default.
• W2891825862 hasConceptScore W2891825862C2780559512 @default.
• W2891825862 hasConceptScore W2891825862C71924100 @default.
• W2891825862 hasIssue "5" @default.
• W2891825862 hasLocation W28918258621 @default.
• W2891825862 hasOpenAccess W2891825862 @default.
• W2891825862 hasPrimaryLocation W28918258621 @default.
• W2891825862 hasRelatedWork W1578613786 @default.
• W2891825862 hasRelatedWork W2024917325 @default.
• W2891825862 hasRelatedWork W2033298711 @default.
• W2891825862 hasRelatedWork W2034276841 @default.
• W2891825862 hasRelatedWork W2048603970 @default.

• next