FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891825965> ?p ?o ?g. }

• W2891825965 endingPage "4911" @default.
• W2891825965 startingPage "4902" @default.
• W2891825965 abstract "Short-chain fatty acids (SCFAs) are the main source of energy for postweaning ruminants. The monocarboxylic acid transporters, MCT1 and MCT4, are thought to contribute to the absorption of SCFAs from the surface of the rumen following weaning. The present study measured changes in MCT1 and MCT4 expression in ruminal epithelial cells isolated from male preweaning (22 to 34 d old, n = 6) and postweaning (55 to 58 d old, n = 8) calves after euthanasia and sought to examine whether SCFAs stimulate the expression of these transporters. In the current study, cluster of differentiation 147 (CD147) gene expression in the rumen was also investigated since CD147 has been considered to act as ancillary protein for MCT1 and MCT4 to express their correct function. The gene expression levels of MCT1, MCT4, and CD147 in the rumen were found to be significantly higher in postweaning calves than in preweaning calves. Strong MCT1 immunoreactivity was detected in both the stratum basale (SB) and the stratum spinosum (SS) in postweaning ruminal epithelium. Expression of MCT1 in preweaning calves was localized to a specific region of the SB and of the SS. MCT4-immunopositive cells were detected in the stratum corneum (SC) of the ruminal epithelium in postweaning calves. However, only a low level of signal was detected in the SC of preweaning animals. Furthermore, in vitro experiments, ruminal epithelial cells were incubated for 24 h with acetate (0.04, 0.4, and 4 mM), propionate (0.2, 2, and 20 mM), butyrate (0.1, 1, and 10 mM), or β-hydroxybutyrate (BHBA; 0.1, 1, and 10 mM), respectively. Both propionate and butyrate induced an increase in the gene expression levels of MCT4 and CD147, but did not affect MCT1 gene expression. There are no significant effects of acetate and BHBA treatment on these gene expressions. Taken together, these results suggest that an increase in MCT4 and CD147 gene expression in the ruminal epithelium of postweaning calves is likely to be due to the effects of propionate and butyrate derived from a solid-based diet, which may contribute to ruminal development following weaning." @default.
• W2891825965 created "2018-09-27" @default.
• W2891825965 creator A5015622454 @default.
• W2891825965 creator A5051606925 @default.
• W2891825965 creator A5054078999 @default.
• W2891825965 creator A5084208131 @default.
• W2891825965 date "2018-09-12" @default.
• W2891825965 modified "2023-10-14" @default.
• W2891825965 title "Propionate and butyrate induce gene expression of monocarboxylate transporter 4 and cluster of differentiation 147 in cultured rumen epithelial cells derived from preweaning dairy calves1" @default.
• W2891825965 cites W1482713284 @default.
• W2891825965 cites W1953702613 @default.
• W2891825965 cites W1963672683 @default.
• W2891825965 cites W1964173392 @default.
• W2891825965 cites W1973391451 @default.
• W2891825965 cites W1983347286 @default.
• W2891825965 cites W1991101913 @default.
• W2891825965 cites W2000117132 @default.
• W2891825965 cites W2001539184 @default.
• W2891825965 cites W2010321425 @default.
• W2891825965 cites W2014364284 @default.
• W2891825965 cites W2016693701 @default.
• W2891825965 cites W2025441873 @default.
• W2891825965 cites W2035421462 @default.
• W2891825965 cites W2037622180 @default.
• W2891825965 cites W2042986750 @default.
• W2891825965 cites W2048001561 @default.
• W2891825965 cites W2052291264 @default.
• W2891825965 cites W2056125595 @default.
• W2891825965 cites W2058204672 @default.
• W2891825965 cites W2061700980 @default.
• W2891825965 cites W2068045057 @default.
• W2891825965 cites W2068655148 @default.
• W2891825965 cites W2079183971 @default.
• W2891825965 cites W2083608694 @default.
• W2891825965 cites W2085651249 @default.
• W2891825965 cites W2091757274 @default.
• W2891825965 cites W2097367048 @default.
• W2891825965 cites W2100195396 @default.
• W2891825965 cites W2105423509 @default.
• W2891825965 cites W2119745850 @default.
• W2891825965 cites W2122372985 @default.
• W2891825965 cites W2123687793 @default.
• W2891825965 cites W2135935504 @default.
• W2891825965 cites W2136199519 @default.
• W2891825965 cites W2137937088 @default.
• W2891825965 cites W2150780140 @default.
• W2891825965 cites W2151683534 @default.
• W2891825965 cites W2154960204 @default.
• W2891825965 cites W2162704444 @default.
• W2891825965 cites W2165235603 @default.
• W2891825965 cites W2200123224 @default.
• W2891825965 cites W2331112192 @default.
• W2891825965 cites W2789383517 @default.
• W2891825965 doi "https://doi.org/10.1093/jas/sky334" @default.
• W2891825965 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6247864" @default.
• W2891825965 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30215729" @default.
• W2891825965 hasPublicationYear "2018" @default.
• W2891825965 type Work @default.
• W2891825965 sameAs 2891825965 @default.
• W2891825965 citedByCount "15" @default.
• W2891825965 countsByYear W28918259652020 @default.
• W2891825965 countsByYear W28918259652021 @default.
• W2891825965 countsByYear W28918259652022 @default.
• W2891825965 countsByYear W28918259652023 @default.
• W2891825965 crossrefType "journal-article" @default.
• W2891825965 hasAuthorship W2891825965A5015622454 @default.
• W2891825965 hasAuthorship W2891825965A5051606925 @default.
• W2891825965 hasAuthorship W2891825965A5054078999 @default.
• W2891825965 hasAuthorship W2891825965A5084208131 @default.
• W2891825965 hasBestOaLocation W28918259652 @default.
• W2891825965 hasConcept C100544194 @default.
• W2891825965 hasConcept C104317684 @default.
• W2891825965 hasConcept C126322002 @default.
• W2891825965 hasConcept C134018914 @default.
• W2891825965 hasConcept C149011108 @default.
• W2891825965 hasConcept C150194340 @default.
• W2891825965 hasConcept C153911025 @default.
• W2891825965 hasConcept C2776979534 @default.
• W2891825965 hasConcept C2778370115 @default.
• W2891825965 hasConcept C2780014933 @default.
• W2891825965 hasConcept C2780655333 @default.
• W2891825965 hasConcept C47089857 @default.
• W2891825965 hasConcept C529295009 @default.
• W2891825965 hasConcept C54355233 @default.
• W2891825965 hasConcept C55493867 @default.
• W2891825965 hasConcept C70262065 @default.
• W2891825965 hasConcept C71924100 @default.
• W2891825965 hasConcept C86803240 @default.
• W2891825965 hasConceptScore W2891825965C100544194 @default.
• W2891825965 hasConceptScore W2891825965C104317684 @default.
• W2891825965 hasConceptScore W2891825965C126322002 @default.
• W2891825965 hasConceptScore W2891825965C134018914 @default.
• W2891825965 hasConceptScore W2891825965C149011108 @default.
• W2891825965 hasConceptScore W2891825965C150194340 @default.
• W2891825965 hasConceptScore W2891825965C153911025 @default.
• W2891825965 hasConceptScore W2891825965C2776979534 @default.
• W2891825965 hasConceptScore W2891825965C2778370115 @default.
• W2891825965 hasConceptScore W2891825965C2780014933 @default.

• next