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- W2891833050 abstract "Examine inhibition of dietary fat absorption with orlistat tablets (24, 36, 48, 72, and 144 mg) vs. 60-mg orlistat capsule.83 overweight/obese subjects randomized to 1 of 6 open-label treatments. Pre- vs. post-treatment fecal fat analysis was conducted.Mean percent fecal fat (60-mg capsule, 16.8%; 48-mg tablet, 16.5%) was similar (ratio of geometric mean and 90% CI: 60-mg capsule/48-mg tablet, 1.05 (0.79, 1.39)). Fecal fat excretion was ~2.5 times greater with 144-mg vs. 24-mg tablets. No new safety concerns emerged.Dietary fat excretion increases with increasing orlistat tablet dose. ." @default.
- W2891833050 created "2018-09-27" @default.
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- W2891833050 date "2018-10-01" @default.
- W2891833050 modified "2023-09-26" @default.
- W2891833050 title "Dose-ranging study of an orlistat tablet formulation" @default.
- W2891833050 doi "https://doi.org/10.5414/cp203191" @default.
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