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- W2891838909 abstract "The aim of this paper is the isolation of individual compounds, which are caused the antibacterial activity of the leaves of the bearberry [Arctostaphylos uva-ursi (L.) Spreng.]. The leaves of Arctostaphylos uva-ursi, collected in Perm region, there were extracted with 70% ethanol, the obtained water-alcoholic infusion there was evaporated in vacuum.By means of the chromatographic methods with the using of silica gel 40/100 and eluent systems (chloroform and ethanol in several ratio) from the evaporated water-alcoholic extract of the leaves of Arctostaphylos uva-ursi, a substance with antibacterial activity, ethyl ester of p-digallic acid, which is a new natural compound, was isolated along with arbutin ((1-О-b-D-glucopyranoside of hydroquinone) from the leaves of this plant. The chemical structures of the ethyl ester of p-digallic acid and arbutin were established with the using of data of 1H-NMR-spectroscopy, UV-spectroscopy and mass-spectrometry..The antibacterial activity of ethyl ester of p-digallic acid against test cultures of gram-positive bacteria Bacillus cereus and Staphylococcus aureus, gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa for the first time was determined. By antibacterial activity, arbutin was inferior not only to ethyl ester of p-digallic acid, but also to decoction from the leaves of the bearberry. Consequently, the ethyl ester of p-digallic acid is one in main component, which is take the contribution in the antibacterial activity of the decoction and other preparations of the leaves of Arctostaphylos uva-ursi." @default.
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- W2891838909 date "2018-02-07" @default.
- W2891838909 modified "2023-09-26" @default.
- W2891838909 title "THE ANTIBACTERIAL ACTIVITY OF COMPOUNDS FROM LEAVES OF ARCTOSTAPHYLOS UVA-URS" @default.
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- W2891838909 doi "https://doi.org/10.14258/jcprm.2018033542" @default.
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