FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891839576> ?p ?o ?g. }

• W2891839576 endingPage "3325" @default.
• W2891839576 startingPage "3317" @default.
• W2891839576 abstract "Porcine reproductive and respiratory syndrome virus (PRRSV) is a pathogen that severely disrupts swine production. Despite sustained efforts, the disease is still endemic, with high mortality and morbidity. New antiviral strategies to control PRRSV are needed. Griffithsin, a red algal lectin, has potent antiviral effect on several human enveloped viruses, but this effect has not been demonstrated on PRRSV. Here, we first tested the in vitro antiviral activity of Griffithsin against PRRSV. Griffithsin exerted strong saccharide-dependent antiviral activity against PRRSV, probably through interactions with glycans on the surface of PRRSV that interfered with virus entry. Furthermore we revealed that Griffithsin’s action on PRRSV involved blocking viral adsorption, and it had no effect on viral penetration. Besides Our findings also suggested that Griffithsin may interfere with cell-to-cell spread to prevent virus transmission. The remarkable potency profile of Griffithsin supports its potential value as an antiviral agent against PRRSV." @default.
• W2891839576 created "2018-09-27" @default.
• W2891839576 creator A5001110219 @default.
• W2891839576 creator A5024815756 @default.
• W2891839576 creator A5034182089 @default.
• W2891839576 creator A5056916842 @default.
• W2891839576 creator A5059712495 @default.
• W2891839576 creator A5071317221 @default.
• W2891839576 date "2018-09-15" @default.
• W2891839576 modified "2023-10-14" @default.
• W2891839576 title "Griffithsin inhibits porcine reproductive and respiratory syndrome virus infection in vitro" @default.
• W2891839576 cites W1977610810 @default.
• W2891839576 cites W1999129896 @default.
• W2891839576 cites W2006845729 @default.
• W2891839576 cites W2008816138 @default.
• W2891839576 cites W2015067929 @default.
• W2891839576 cites W2019522897 @default.
• W2891839576 cites W2021919859 @default.
• W2891839576 cites W2031869301 @default.
• W2891839576 cites W2031912374 @default.
• W2891839576 cites W2055030001 @default.
• W2891839576 cites W2060270933 @default.
• W2891839576 cites W2065243148 @default.
• W2891839576 cites W2075391258 @default.
• W2891839576 cites W2098337603 @default.
• W2891839576 cites W2102090534 @default.
• W2891839576 cites W2117770375 @default.
• W2891839576 cites W2150924565 @default.
• W2891839576 cites W2151678945 @default.
• W2891839576 cites W2154097024 @default.
• W2891839576 cites W2238130276 @default.
• W2891839576 cites W2272574791 @default.
• W2891839576 cites W2296098023 @default.
• W2891839576 cites W232721668 @default.
• W2891839576 cites W2341964544 @default.
• W2891839576 cites W2419247485 @default.
• W2891839576 cites W2505744648 @default.
• W2891839576 cites W2532457307 @default.
• W2891839576 cites W2550958141 @default.
• W2891839576 cites W2747560763 @default.
• W2891839576 cites W2768832836 @default.
• W2891839576 cites W575415440 @default.
• W2891839576 doi "https://doi.org/10.1007/s00705-018-4029-x" @default.
• W2891839576 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7087274" @default.
• W2891839576 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30220033" @default.
• W2891839576 hasPublicationYear "2018" @default.
• W2891839576 type Work @default.
• W2891839576 sameAs 2891839576 @default.
• W2891839576 citedByCount "8" @default.
• W2891839576 countsByYear W28918395762019 @default.
• W2891839576 countsByYear W28918395762020 @default.
• W2891839576 countsByYear W28918395762021 @default.
• W2891839576 countsByYear W28918395762022 @default.
• W2891839576 countsByYear W28918395762023 @default.
• W2891839576 crossrefType "journal-article" @default.
• W2891839576 hasAuthorship W2891839576A5001110219 @default.
• W2891839576 hasAuthorship W2891839576A5024815756 @default.
• W2891839576 hasAuthorship W2891839576A5034182089 @default.
• W2891839576 hasAuthorship W2891839576A5056916842 @default.
• W2891839576 hasAuthorship W2891839576A5059712495 @default.
• W2891839576 hasAuthorship W2891839576A5071317221 @default.
• W2891839576 hasBestOaLocation W28918395761 @default.
• W2891839576 hasConcept C140704245 @default.
• W2891839576 hasConcept C159047783 @default.
• W2891839576 hasConcept C202751555 @default.
• W2891839576 hasConcept C2522874641 @default.
• W2891839576 hasConcept C2776460866 @default.
• W2891839576 hasConcept C2779819720 @default.
• W2891839576 hasConcept C55493867 @default.
• W2891839576 hasConcept C58475186 @default.
• W2891839576 hasConcept C86803240 @default.
• W2891839576 hasConcept C89423630 @default.
• W2891839576 hasConcept C97380033 @default.
• W2891839576 hasConceptScore W2891839576C140704245 @default.
• W2891839576 hasConceptScore W2891839576C159047783 @default.
• W2891839576 hasConceptScore W2891839576C202751555 @default.
• W2891839576 hasConceptScore W2891839576C2522874641 @default.
• W2891839576 hasConceptScore W2891839576C2776460866 @default.
• W2891839576 hasConceptScore W2891839576C2779819720 @default.
• W2891839576 hasConceptScore W2891839576C55493867 @default.
• W2891839576 hasConceptScore W2891839576C58475186 @default.
• W2891839576 hasConceptScore W2891839576C86803240 @default.
• W2891839576 hasConceptScore W2891839576C89423630 @default.
• W2891839576 hasConceptScore W2891839576C97380033 @default.
• W2891839576 hasIssue "12" @default.
• W2891839576 hasLocation W28918395761 @default.
• W2891839576 hasLocation W28918395762 @default.
• W2891839576 hasLocation W28918395763 @default.
• W2891839576 hasLocation W28918395764 @default.
• W2891839576 hasOpenAccess W2891839576 @default.
• W2891839576 hasPrimaryLocation W28918395761 @default.
• W2891839576 hasRelatedWork W2000086867 @default.
• W2891839576 hasRelatedWork W2006589005 @default.
• W2891839576 hasRelatedWork W2043069531 @default.
• W2891839576 hasRelatedWork W2984636550 @default.
• W2891839576 hasRelatedWork W3033251622 @default.
• W2891839576 hasRelatedWork W3162370640 @default.
• W2891839576 hasRelatedWork W3213098735 @default.

• next