FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891845142> ?p ?o ?g. }

• W2891845142 endingPage "63" @default.
• W2891845142 startingPage "54" @default.
• W2891845142 abstract "A mathematical model was developed to predict the transport of sumatriptan molecules across the skin followed by absorption into the bloodstream. The drug was encapsulated in dissolving polyvinylpyrrolidone-based microneedles shaped in the form of pyramids. Mass balance equations were derived to simulate the dissolution and transport of the pharmaceutical ingredient. The theoretical framework made it possible to assess and predict the effects of key parameters on the release profile. The skin concentration increased with the loading dose and the height of the microneedle. An inverse relationship was noted between the amount of drug released in the dermal layer and the pitch width. These results were validated with in-vitro diffusion studies previously conducted using Göttingen minipig skin. The new mathematical approach successfully explained the in-vitro permeation of three different sumatriptan-containing formulations." @default.
• W2891845142 created "2018-09-27" @default.
• W2891845142 creator A5008102361 @default.
• W2891845142 creator A5065539472 @default.
• W2891845142 creator A5076625976 @default.
• W2891845142 creator A5086379062 @default.
• W2891845142 date "2018-12-01" @default.
• W2891845142 modified "2023-09-27" @default.
• W2891845142 title "Modelling the in-vitro dissolution and release of sumatriptan succinate from polyvinylpyrrolidone-based microneedles" @default.
• W2891845142 cites W1903010132 @default.
• W2891845142 cites W1971583510 @default.
• W2891845142 cites W1973866150 @default.
• W2891845142 cites W1981760171 @default.
• W2891845142 cites W2013315584 @default.
• W2891845142 cites W2040900349 @default.
• W2891845142 cites W2043308790 @default.
• W2891845142 cites W2048388328 @default.
• W2891845142 cites W2054271813 @default.
• W2891845142 cites W2054294261 @default.
• W2891845142 cites W2060929621 @default.
• W2891845142 cites W2061383087 @default.
• W2891845142 cites W2080430067 @default.
• W2891845142 cites W2086139738 @default.
• W2891845142 cites W2089143024 @default.
• W2891845142 cites W2090155464 @default.
• W2891845142 cites W2093014785 @default.
• W2891845142 cites W2116182190 @default.
• W2891845142 cites W2155591650 @default.
• W2891845142 cites W2159403770 @default.
• W2891845142 cites W2328984514 @default.
• W2891845142 cites W2335972983 @default.
• W2891845142 cites W2587861573 @default.
• W2891845142 cites W2605792741 @default.
• W2891845142 cites W2775215939 @default.
• W2891845142 cites W374314792 @default.
• W2891845142 cites W4240821889 @default.
• W2891845142 doi "https://doi.org/10.1016/j.ejps.2018.09.010" @default.
• W2891845142 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30223035" @default.
• W2891845142 hasPublicationYear "2018" @default.
• W2891845142 type Work @default.
• W2891845142 sameAs 2891845142 @default.
• W2891845142 citedByCount "22" @default.
• W2891845142 countsByYear W28918451422019 @default.
• W2891845142 countsByYear W28918451422020 @default.
• W2891845142 countsByYear W28918451422021 @default.
• W2891845142 countsByYear W28918451422022 @default.
• W2891845142 countsByYear W28918451422023 @default.
• W2891845142 crossrefType "journal-article" @default.
• W2891845142 hasAuthorship W2891845142A5008102361 @default.
• W2891845142 hasAuthorship W2891845142A5065539472 @default.
• W2891845142 hasAuthorship W2891845142A5076625976 @default.
• W2891845142 hasAuthorship W2891845142A5086379062 @default.
• W2891845142 hasConcept C121332964 @default.
• W2891845142 hasConcept C125287762 @default.
• W2891845142 hasConcept C136229726 @default.
• W2891845142 hasConcept C14029885 @default.
• W2891845142 hasConcept C159985019 @default.
• W2891845142 hasConcept C170493617 @default.
• W2891845142 hasConcept C178790620 @default.
• W2891845142 hasConcept C185592680 @default.
• W2891845142 hasConcept C188027245 @default.
• W2891845142 hasConcept C192562407 @default.
• W2891845142 hasConcept C202751555 @default.
• W2891845142 hasConcept C2778871607 @default.
• W2891845142 hasConcept C2778938600 @default.
• W2891845142 hasConcept C2779484521 @default.
• W2891845142 hasConcept C2780077769 @default.
• W2891845142 hasConcept C2781430271 @default.
• W2891845142 hasConcept C3019981671 @default.
• W2891845142 hasConcept C41625074 @default.
• W2891845142 hasConcept C43617362 @default.
• W2891845142 hasConcept C50670333 @default.
• W2891845142 hasConcept C55493867 @default.
• W2891845142 hasConcept C69357855 @default.
• W2891845142 hasConcept C71924100 @default.
• W2891845142 hasConcept C88380143 @default.
• W2891845142 hasConcept C97355855 @default.
• W2891845142 hasConcept C98274493 @default.
• W2891845142 hasConceptScore W2891845142C121332964 @default.
• W2891845142 hasConceptScore W2891845142C125287762 @default.
• W2891845142 hasConceptScore W2891845142C136229726 @default.
• W2891845142 hasConceptScore W2891845142C14029885 @default.
• W2891845142 hasConceptScore W2891845142C159985019 @default.
• W2891845142 hasConceptScore W2891845142C170493617 @default.
• W2891845142 hasConceptScore W2891845142C178790620 @default.
• W2891845142 hasConceptScore W2891845142C185592680 @default.
• W2891845142 hasConceptScore W2891845142C188027245 @default.
• W2891845142 hasConceptScore W2891845142C192562407 @default.
• W2891845142 hasConceptScore W2891845142C202751555 @default.
• W2891845142 hasConceptScore W2891845142C2778871607 @default.
• W2891845142 hasConceptScore W2891845142C2778938600 @default.
• W2891845142 hasConceptScore W2891845142C2779484521 @default.
• W2891845142 hasConceptScore W2891845142C2780077769 @default.
• W2891845142 hasConceptScore W2891845142C2781430271 @default.
• W2891845142 hasConceptScore W2891845142C3019981671 @default.
• W2891845142 hasConceptScore W2891845142C41625074 @default.
• W2891845142 hasConceptScore W2891845142C43617362 @default.
• W2891845142 hasConceptScore W2891845142C50670333 @default.

• next