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- W2891847266 abstract "Primary hyperaldosteronism is the most common cause of secondary hypertension and endocrine-related hypertension and is characterized by autonomous, inappropriately elevated serum aldosterone, arising from either an aldosterone producing adenoma or bilateral adrenal hyperplasia. In comparison to matched patients with primary (essential) hypertension, patients with both subtypes of primary hyperaldosteronism have increased odds of stroke, non-fatal heart attack and atrial fibrillation. Moreover, patients with primary hyperaldosteronism have worse psychosocial and quality of life scores when compared to patients with primary hypertension. Although treatment guidelines for primary hyperaldosteronism vary, diagnosis is usually focused on identifying serum hyperaldosteronism and subsequently by differentiating between unilateral and bilateral disease with imaging (CT or MRI) and/or adrenal-venous sampling. Most patients with aldosterone producing adenoma can be managed successfully with laparoscopic adrenalectomy, not only by curing their hypertension, but also by reversing cardiovascular and renal complications. Moreover, primary hyperaldosteronism patients diagnosed with bilateral-adrenal hyperplasia can likewise have improvement in hypertension and downstream cardiovascular outcomes with appropriate mineralocorticoid-receptor antagonist treatment." @default.
- W2891847266 created "2018-09-27" @default.
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- W2891847266 date "2018-01-01" @default.
- W2891847266 modified "2023-09-27" @default.
- W2891847266 title "Routine Screening for Primary Hyperaldosteronism in Hypertensive Patients: Yes or No?" @default.
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- W2891847266 doi "https://doi.org/10.1007/978-3-319-92860-9_27" @default.
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