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• W2891864602 abstract "Abstract Clinicians continue to rely on invasive tissue biopsies as a mean to assess a patient's disease and prescribe appropriate treatment regimens. Biopsies not only are risky and expensive but also limit the understanding of disease. Circulating tumor cells (CTCs) can be isolated from a simple blood draw and offer a promising potential to both diagnose and monitor cancer progression. The VTX‐1 Liquid Biopsy System automates the isolation of clinically relevant CTC populations, while simplifying their collection for easy analysis, ultimately expanding the clinical possibilities for CTCs. We present here the key features and performance of this automated system for isolating CTCs directly from whole blood, both with cell spiking experiments and patient samples. As a first step toward the characterization of CTCs for research applications and transfer to clinical practice, we present workflows for both molecular analyses and automated cell enumeration and biomarker quantification with the BioView imaging platform. © 2018 The Authors. Cytometry Part A published by Wiley Periodicals, Inc. on behalf of International Society for Advancement of Cytometry." @default.
• W2891864602 created "2018-09-27" @default.
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• W2891864602 date "2018-09-13" @default.
• W2891864602 modified "2023-09-30" @default.
• W2891864602 title "VTX‐1 Liquid Biopsy System for Fully‐Automated and Label‐Free Isolation of Circulating Tumor Cells with Automated Enumeration by BioView Platform" @default.
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• W2891864602 doi "https://doi.org/10.1002/cyto.a.23592" @default.
• W2891864602 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6585822" @default.
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