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- W2891879533 abstract "ChemistryChemists spend a great deal of time tweaking the conditions of known reactions. Small changes to temperature and concentration can have a big influence over product yield. Bedard et al. present a flow-based reaction platform that carries out this laborious task automatically. By using feedback from integrated analytics, the system converges on optimal conditions that can then be applied with high precision afterward. A series of modules with heating, cooling, mixing, and photochemical capabilities could be configured for a broad range of reactions. These include homogeneous and heterogeneous palladium-catalyzed cross-coupling, reductive amination, and the generation of sensitive intermediates under an inert atmosphere.Science , this issue p. [1220][1] [1]: /lookup/doi/10.1126/science.aat0650" @default.
- W2891879533 created "2018-09-27" @default.
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- W2891879533 date "2018-09-20" @default.
- W2891879533 modified "2023-10-14" @default.
- W2891879533 title "A self-optimizing reactor" @default.
- W2891879533 doi "https://doi.org/10.1126/science.361.6408.1211-c" @default.
- W2891879533 hasPublicationYear "2018" @default.
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