FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891887155> ?p ?o ?g. }

• W2891887155 endingPage "3268" @default.
• W2891887155 startingPage "3259" @default.
• W2891887155 abstract "Purpose To provide evidence-based consensus recommendations on choice of end points for clinical trials in metastatic breast cancer, with a focus on biologic subtype and line of therapy. Methods The National Cancer Institute Breast Cancer Steering Committee convened a working group of breast medical oncologists, patient advocates, biostatisticians, and liaisons from the Food and Drug Administration to conduct a detailed curated systematic review of the literature, including original reports, reviews, and meta-analyses, to determine the current landscape of therapeutic options, recent clinical trial data, and natural history of four biologic subtypes of breast cancer. Ongoing clinical trials for metastatic breast cancer in each subtype also were reviewed from ClinicalTrials.gov for planned primary end points. External input was obtained from the pharmaceutic/biotechnology industry, real-world clinical data specialists, experts in quality of life and patient-reported outcomes, and combined metrics for assessing magnitude of clinical benefit. Results The literature search yielded 146 publications to inform the recommendations from the working group. Conclusion Recommendations for appropriate end points for metastatic breast cancer clinical trials focus on biologic subtype and line of therapy and the magnitude of absolute and relative gains that would represent meaningful clinical benefit." @default.
• W2891887155 created "2018-09-27" @default.
• W2891887155 creator A5002068827 @default.
• W2891887155 creator A5004000071 @default.
• W2891887155 creator A5006471068 @default.
• W2891887155 creator A5010952325 @default.
• W2891887155 creator A5017334876 @default.
• W2891887155 creator A5020083811 @default.
• W2891887155 creator A5028764986 @default.
• W2891887155 creator A5033078993 @default.
• W2891887155 creator A5033831143 @default.
• W2891887155 creator A5037198503 @default.
• W2891887155 creator A5053485955 @default.
• W2891887155 creator A5062916090 @default.
• W2891887155 creator A5071749616 @default.
• W2891887155 creator A5074479466 @default.
• W2891887155 creator A5078509618 @default.
• W2891887155 creator A5081974715 @default.
• W2891887155 creator A5091772334 @default.
• W2891887155 date "2018-11-10" @default.
• W2891887155 modified "2023-10-01" @default.
• W2891887155 title "National Cancer Institute Breast Cancer Steering Committee Working Group Report on Meaningful and Appropriate End Points for Clinical Trials in Metastatic Breast Cancer" @default.
• W2891887155 cites W1464936406 @default.
• W2891887155 cites W1971159432 @default.
• W2891887155 cites W1973504138 @default.
• W2891887155 cites W1989268854 @default.
• W2891887155 cites W2090295250 @default.
• W2891887155 cites W2093215461 @default.
• W2891887155 cites W2095156669 @default.
• W2891887155 cites W2096027508 @default.
• W2891887155 cites W2096864872 @default.
• W2891887155 cites W2097216790 @default.
• W2891887155 cites W2097698108 @default.
• W2891887155 cites W2104389711 @default.
• W2891887155 cites W2110647409 @default.
• W2891887155 cites W2115602788 @default.
• W2891887155 cites W2132620319 @default.
• W2891887155 cites W2134119471 @default.
• W2891887155 cites W2134539328 @default.
• W2891887155 cites W2135403187 @default.
• W2891887155 cites W2136919572 @default.
• W2891887155 cites W2137228442 @default.
• W2891887155 cites W2137620209 @default.
• W2891887155 cites W2140055441 @default.
• W2891887155 cites W2142257518 @default.
• W2891887155 cites W2143937001 @default.
• W2891887155 cites W2144915560 @default.
• W2891887155 cites W2154514789 @default.
• W2891887155 cites W2156677665 @default.
• W2891887155 cites W2158679766 @default.
• W2891887155 cites W2159967578 @default.
• W2891887155 cites W2167188058 @default.
• W2891887155 cites W2338977782 @default.
• W2891887155 cites W2346624277 @default.
• W2891887155 cites W2413971556 @default.
• W2891887155 cites W2467898110 @default.
• W2891887155 cites W2528767298 @default.
• W2891887155 cites W2534459715 @default.
• W2891887155 cites W2552099557 @default.
• W2891887155 cites W2620993107 @default.
• W2891887155 cites W2763875663 @default.
• W2891887155 cites W2772986641 @default.
• W2891887155 cites W2793000264 @default.
• W2891887155 cites W2793539832 @default.
• W2891887155 cites W4250992282 @default.
• W2891887155 doi "https://doi.org/10.1200/jco.18.00242" @default.
• W2891887155 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7351338" @default.
• W2891887155 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30212295" @default.
• W2891887155 hasPublicationYear "2018" @default.
• W2891887155 type Work @default.
• W2891887155 sameAs 2891887155 @default.
• W2891887155 citedByCount "17" @default.
• W2891887155 countsByYear W28918871552019 @default.
• W2891887155 countsByYear W28918871552020 @default.
• W2891887155 countsByYear W28918871552021 @default.
• W2891887155 countsByYear W28918871552022 @default.
• W2891887155 countsByYear W28918871552023 @default.
• W2891887155 crossrefType "journal-article" @default.
• W2891887155 hasAuthorship W2891887155A5002068827 @default.
• W2891887155 hasAuthorship W2891887155A5004000071 @default.
• W2891887155 hasAuthorship W2891887155A5006471068 @default.
• W2891887155 hasAuthorship W2891887155A5010952325 @default.
• W2891887155 hasAuthorship W2891887155A5017334876 @default.
• W2891887155 hasAuthorship W2891887155A5020083811 @default.
• W2891887155 hasAuthorship W2891887155A5028764986 @default.
• W2891887155 hasAuthorship W2891887155A5033078993 @default.
• W2891887155 hasAuthorship W2891887155A5033831143 @default.
• W2891887155 hasAuthorship W2891887155A5037198503 @default.
• W2891887155 hasAuthorship W2891887155A5053485955 @default.
• W2891887155 hasAuthorship W2891887155A5062916090 @default.
• W2891887155 hasAuthorship W2891887155A5071749616 @default.
• W2891887155 hasAuthorship W2891887155A5074479466 @default.
• W2891887155 hasAuthorship W2891887155A5078509618 @default.
• W2891887155 hasAuthorship W2891887155A5081974715 @default.
• W2891887155 hasAuthorship W2891887155A5091772334 @default.
• W2891887155 hasBestOaLocation W28918871552 @default.
• W2891887155 hasConcept C121608353 @default.
• W2891887155 hasConcept C126322002 @default.

• next