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• W2891896056 abstract "Aim To evaluate trends in admission temperature and its effect on mortality and short‐term morbidities in extremely preterm infants. Methods A regional cohort study of infants born at 23–28 weeks’ gestation and admitted to the 10 neonatal intensive care units in New South Wales and the Australian Capital Territory between 1994 and 2012. Hypothermia was defined as skin temperature <36°C on admission to the neonatal intensive care unit. The primary outcome was hospital mortality. Results In total, 6267 infants were included. Mean admission temperatures improved significantly from 35.6°C in 1994 to 36.4°C in 2012 ( R < 0.88). The incidence of hypothermia was 29.5 and 13.9% between 1994–2005 and 2006–2012, respectively. In comparison with normothermic infants, hypothermic infants had lower gestational age at birth (26 vs. 27 weeks) and lower birthweight (800 vs. 976 g). In‐hospital mortality was higher in hypothermic infants (28.5 vs. 12.9%; odds ratio (OR) 2.69, 95% confidence interval (CI) 2.37–3.06). Severe intraventricular haemorrhage (12.1 vs. 8.5%, OR 1.48, 95% CI 1.25–1.75), necrotising enterocolitis (NEC) (11.0 vs. 7.5%; OR 1.54, 95% CI 1.29–1.83) and severe retinopathy of prematurity (16.5 vs. 8.9%; OR 2.02, 95% CI 1.70–2.39) were significantly higher in hypothermic infants. Multivariate regression analysis showed hypothermia was an independent risk factor for increased mortality (AOR (adjusted odds ratio ) 1.50, 95% CI 1.29–1.74, P < 0.001) and NEC (AOR 1.28, 95% CI 1.05–1.55, P = 0.01). Conclusions Admission temperatures improved during the time period. Hypothermia at admission was associated with a significant increase in mortality and NEC." @default.
• W2891896056 created "2018-09-27" @default.
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• W2891896056 date "2018-09-15" @default.
• W2891896056 modified "2023-10-11" @default.
• W2891896056 title "Admission temperature and hospital outcomes in extremely preterm infants" @default.
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• W2891896056 doi "https://doi.org/10.1111/jpc.14187" @default.
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