Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891897076> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2891897076 abstract "Introduction: Arterial calcification(AC) is a significant contributor to cardiovascular mortality in patients with chronic kidney disease. We previously reported that heat shock protein 70 (HSP70) induction can inhibit vascular smooth muscle cell calcification. Mitochondrial complexes II, IV, NADH cytochrome c reductase, and cytochrome c oxidase activities were preserved by HSP70 induction leading to reduced apoptosis and RUNX2 expression. The molecular mechanisms of HSP70 vasculo-protective effects involving mitochondrial fusion regulation are currently unknown. Hypothesis: The goal of the present study was to investigate the transcriptomic profile of genes involved in mitochondrial function and vasculo-protective mechanisms of HSPs in AC. Methods: Human arteries were collected from healthy (n=15) and CKD (n=15) patients. AC was analyzed by Alizarin Red. Primary Human aortic endothelial cells (HAECs) was treated in calcification medium (CM: 5mM β-glycerolphosphate + 5mM CaCl2) in time-course experiments ..." @default.
- W2891897076 created "2018-09-27" @default.
- W2891897076 creator A5017065981 @default.
- W2891897076 creator A5017570289 @default.
- W2891897076 creator A5047820165 @default.
- W2891897076 creator A5073420054 @default.
- W2891897076 date "2017-11-14" @default.
- W2891897076 modified "2023-09-23" @default.
- W2891897076 title "Abstract 16123: Transcriptomic Profiling of Mitochondrial Dysfunction That Occurs in Arterial Calcification" @default.
- W2891897076 hasPublicationYear "2017" @default.
- W2891897076 type Work @default.
- W2891897076 sameAs 2891897076 @default.
- W2891897076 citedByCount "0" @default.
- W2891897076 crossrefType "journal-article" @default.
- W2891897076 hasAuthorship W2891897076A5017065981 @default.
- W2891897076 hasAuthorship W2891897076A5017570289 @default.
- W2891897076 hasAuthorship W2891897076A5047820165 @default.
- W2891897076 hasAuthorship W2891897076A5073420054 @default.
- W2891897076 hasConcept C104317684 @default.
- W2891897076 hasConcept C126322002 @default.
- W2891897076 hasConcept C134018914 @default.
- W2891897076 hasConcept C142724271 @default.
- W2891897076 hasConcept C150194340 @default.
- W2891897076 hasConcept C162317418 @default.
- W2891897076 hasConcept C205260736 @default.
- W2891897076 hasConcept C2779395532 @default.
- W2891897076 hasConcept C2780091579 @default.
- W2891897076 hasConcept C2780309369 @default.
- W2891897076 hasConcept C28859421 @default.
- W2891897076 hasConcept C29311851 @default.
- W2891897076 hasConcept C2992686903 @default.
- W2891897076 hasConcept C55493867 @default.
- W2891897076 hasConcept C68991219 @default.
- W2891897076 hasConcept C71924100 @default.
- W2891897076 hasConcept C86803240 @default.
- W2891897076 hasConcept C95444343 @default.
- W2891897076 hasConcept C9832595 @default.
- W2891897076 hasConceptScore W2891897076C104317684 @default.
- W2891897076 hasConceptScore W2891897076C126322002 @default.
- W2891897076 hasConceptScore W2891897076C134018914 @default.
- W2891897076 hasConceptScore W2891897076C142724271 @default.
- W2891897076 hasConceptScore W2891897076C150194340 @default.
- W2891897076 hasConceptScore W2891897076C162317418 @default.
- W2891897076 hasConceptScore W2891897076C205260736 @default.
- W2891897076 hasConceptScore W2891897076C2779395532 @default.
- W2891897076 hasConceptScore W2891897076C2780091579 @default.
- W2891897076 hasConceptScore W2891897076C2780309369 @default.
- W2891897076 hasConceptScore W2891897076C28859421 @default.
- W2891897076 hasConceptScore W2891897076C29311851 @default.
- W2891897076 hasConceptScore W2891897076C2992686903 @default.
- W2891897076 hasConceptScore W2891897076C55493867 @default.
- W2891897076 hasConceptScore W2891897076C68991219 @default.
- W2891897076 hasConceptScore W2891897076C71924100 @default.
- W2891897076 hasConceptScore W2891897076C86803240 @default.
- W2891897076 hasConceptScore W2891897076C95444343 @default.
- W2891897076 hasConceptScore W2891897076C9832595 @default.
- W2891897076 hasLocation W28918970761 @default.
- W2891897076 hasOpenAccess W2891897076 @default.
- W2891897076 hasPrimaryLocation W28918970761 @default.
- W2891897076 hasRelatedWork W1595862626 @default.
- W2891897076 hasRelatedWork W180249622 @default.
- W2891897076 hasRelatedWork W1997639995 @default.
- W2891897076 hasRelatedWork W2042137708 @default.
- W2891897076 hasRelatedWork W2056713878 @default.
- W2891897076 hasRelatedWork W2074710857 @default.
- W2891897076 hasRelatedWork W2117205119 @default.
- W2891897076 hasRelatedWork W2118444721 @default.
- W2891897076 hasRelatedWork W2151495088 @default.
- W2891897076 hasRelatedWork W2166923989 @default.
- W2891897076 hasRelatedWork W2177819816 @default.
- W2891897076 hasRelatedWork W2294362659 @default.
- W2891897076 hasRelatedWork W2335300899 @default.
- W2891897076 hasRelatedWork W2409734102 @default.
- W2891897076 hasRelatedWork W2551020171 @default.
- W2891897076 hasRelatedWork W2561599295 @default.
- W2891897076 hasRelatedWork W2769802276 @default.
- W2891897076 hasRelatedWork W2898969463 @default.
- W2891897076 hasRelatedWork W2972905022 @default.
- W2891897076 hasRelatedWork W3000483740 @default.
- W2891897076 isParatext "false" @default.
- W2891897076 isRetracted "false" @default.
- W2891897076 magId "2891897076" @default.
- W2891897076 workType "article" @default.