FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891902613> ?p ?o ?g. }

• W2891902613 endingPage "632" @default.
• W2891902613 startingPage "622" @default.
• W2891902613 abstract "Insulin regulates fatty acids (FAs) in the blood; conversely, FAs may mediate insulin sensitivity and are potentially modifiable risk factors of the diabetogenic state.The objective of our study was to examine the associations between plasma concentrations of FAs, fasting plasma glucose (FPG), and glycated hemoglobin (HbA1c) among individuals (n = 1433) in the NHANES (2003-2004).Plasma concentrations of 24 individual FAs were considered individually and in subgroups, per chemical structure. Study participants were categorized in diabetogenic groups: Group 1 (HbA1c ≥6.5% or FPG ≥126 mg/dL), Group 2 (HbA1c 5.7% to <6.5% or FPG 100 to <126 mg/dL), and Group 3 (HbA1c <5.7% and FPG <100 mg/dL). We assessed associations between diabetogenic groups and plasma FAs in multivariate multinomial regressions (with Group 3 as the reference).Overall, 7.0% of study participants were in Group 1; 33.3% were in Group 2. Plasma concentrations of several individual FAs, including even-chain saturated FAs (SFAs; myristic, palmitic, stearic acids) and monounsaturated FAs (MUFAs; cis-vaccenic, oleic acids), were respectively associated with greater odds of Groups 1 and 2 status, adjusting for covariates. Higher concentrations of SFA and MUFA subgroups (highest compared with lowest quartile) were associated with increased odds of Group 2 status [SFAs adjusted OR (aOR): 1.51 (95% CI: 1.05, 2.18); MUFAs aOR: 1.78 (95% CI: 1.11, 2.85)]. Higher eicosapentaenoic acid plasma concentration was associated with decreased odds of Group 1 status [quartile 4 aOR: 0.41 (95% CI: 0.17, 0.95)].Higher plasma concentrations of SFAs and MUFAs, primary de novo lipogenesis products, were associated with elevated FPG and HbA1c in a nationally representative study population in the United States. Additional studies are necessary to elucidate potential causal relationships between FAs (from endogenous production and dietary consumption) and diabetogenic indicators, as well as clinical implications for managing diabetes and prediabetes." @default.
• W2891902613 created "2018-09-27" @default.
• W2891902613 creator A5047124475 @default.
• W2891902613 creator A5058282292 @default.
• W2891902613 creator A5066531113 @default.
• W2891902613 date "2018-09-01" @default.
• W2891902613 modified "2023-10-10" @default.
• W2891902613 title "Plasma fatty acids in de novo lipogenesis pathway are associated with diabetogenic indicators among adults: NHANES 2003–2004" @default.
• W2891902613 cites W1588989558 @default.
• W2891902613 cites W1850330438 @default.
• W2891902613 cites W1955662609 @default.
• W2891902613 cites W1969734540 @default.
• W2891902613 cites W1973429542 @default.
• W2891902613 cites W1990251709 @default.
• W2891902613 cites W1993540550 @default.
• W2891902613 cites W2011277021 @default.
• W2891902613 cites W2014887370 @default.
• W2891902613 cites W2016294281 @default.
• W2891902613 cites W2038459882 @default.
• W2891902613 cites W2041510403 @default.
• W2891902613 cites W2045242418 @default.
• W2891902613 cites W2047399305 @default.
• W2891902613 cites W2050372974 @default.
• W2891902613 cites W2059842910 @default.
• W2891902613 cites W2072063152 @default.
• W2891902613 cites W2086480881 @default.
• W2891902613 cites W2086943531 @default.
• W2891902613 cites W2104468045 @default.
• W2891902613 cites W2106011725 @default.
• W2891902613 cites W2119566622 @default.
• W2891902613 cites W2122248435 @default.
• W2891902613 cites W2125895299 @default.
• W2891902613 cites W2126327417 @default.
• W2891902613 cites W2167371554 @default.
• W2891902613 cites W2168530080 @default.
• W2891902613 cites W2171943141 @default.
• W2891902613 cites W2298136869 @default.
• W2891902613 cites W2408797596 @default.
• W2891902613 cites W2414466164 @default.
• W2891902613 cites W2482481232 @default.
• W2891902613 cites W2486972204 @default.
• W2891902613 cites W2526562814 @default.
• W2891902613 cites W2571799777 @default.
• W2891902613 cites W2611848952 @default.
• W2891902613 cites W2617856138 @default.
• W2891902613 cites W2745195379 @default.
• W2891902613 cites W2761254197 @default.
• W2891902613 cites W2785623720 @default.
• W2891902613 cites W4212929213 @default.
• W2891902613 cites W4242844849 @default.
• W2891902613 doi "https://doi.org/10.1093/ajcn/nqy165" @default.
• W2891902613 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6915820" @default.
• W2891902613 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30535092" @default.
• W2891902613 hasPublicationYear "2018" @default.
• W2891902613 type Work @default.
• W2891902613 sameAs 2891902613 @default.
• W2891902613 citedByCount "8" @default.
• W2891902613 countsByYear W28919026132019 @default.
• W2891902613 countsByYear W28919026132020 @default.
• W2891902613 countsByYear W28919026132021 @default.
• W2891902613 countsByYear W28919026132022 @default.
• W2891902613 countsByYear W28919026132023 @default.
• W2891902613 crossrefType "journal-article" @default.
• W2891902613 hasAuthorship W2891902613A5047124475 @default.
• W2891902613 hasAuthorship W2891902613A5058282292 @default.
• W2891902613 hasAuthorship W2891902613A5066531113 @default.
• W2891902613 hasBestOaLocation W28919026131 @default.
• W2891902613 hasConcept C126322002 @default.
• W2891902613 hasConcept C134018914 @default.
• W2891902613 hasConcept C156957248 @default.
• W2891902613 hasConcept C185592680 @default.
• W2891902613 hasConcept C2779874844 @default.
• W2891902613 hasConcept C2779936771 @default.
• W2891902613 hasConcept C2908647359 @default.
• W2891902613 hasConcept C44249647 @default.
• W2891902613 hasConcept C543025807 @default.
• W2891902613 hasConcept C55493867 @default.
• W2891902613 hasConcept C68443243 @default.
• W2891902613 hasConcept C71924100 @default.
• W2891902613 hasConcept C99454951 @default.
• W2891902613 hasConceptScore W2891902613C126322002 @default.
• W2891902613 hasConceptScore W2891902613C134018914 @default.
• W2891902613 hasConceptScore W2891902613C156957248 @default.
• W2891902613 hasConceptScore W2891902613C185592680 @default.
• W2891902613 hasConceptScore W2891902613C2779874844 @default.
• W2891902613 hasConceptScore W2891902613C2779936771 @default.
• W2891902613 hasConceptScore W2891902613C2908647359 @default.
• W2891902613 hasConceptScore W2891902613C44249647 @default.
• W2891902613 hasConceptScore W2891902613C543025807 @default.
• W2891902613 hasConceptScore W2891902613C55493867 @default.
• W2891902613 hasConceptScore W2891902613C68443243 @default.
• W2891902613 hasConceptScore W2891902613C71924100 @default.
• W2891902613 hasConceptScore W2891902613C99454951 @default.
• W2891902613 hasFunder F4320337357 @default.
• W2891902613 hasIssue "3" @default.
• W2891902613 hasLocation W28919026131 @default.
• W2891902613 hasLocation W28919026132 @default.
• W2891902613 hasLocation W28919026133 @default.

• next