Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891918534> ?p ?o ?g. }
- W2891918534 endingPage "1957" @default.
- W2891918534 startingPage "1957" @default.
- W2891918534 abstract "The Amazon River basin is the largest tropical forest in the world. Most of the Amazon belongs to Brazil, a developing country that currently faces huge challenges related to the consolidation of its universal healthcare system. Noncommunicable diseases (NCDs) are the leading cause of death in Brazil, accounting for 74% of all deaths, and NCDs are probably underestimated in Amazonian population because of their geographical isolation and the precariousness of riverine communities. Important risk factors, such as genetic susceptibility, remain undetermined in the riverine population. This study performed fasting blood sugar (FBS) and blood pressure measurements and investigated the presence of the ε4 allele of apolipoprotein E (APOE4) to determine the prevalence of diabetes, hypertension and the genetic risk of NCDs. FBS and APOE4 were measured in blood samples from 763 participants using spectrometry and real-time PCR; 67.5% showed altered measurements, and 57.9% had never been diagnosed or treated. Altered FBS was found in 28.3% of the participants, hypertension in 57.6% and APOE4 in 32.0%. The health profile of the riverine population appears to differ from that of urban population in the Amazon. Additional risk factors for NCDs, such as environmental contamination and nutritional transition, may contribute more than increased genetic susceptibility to the prevalence of altered FBS and hypertension. Our results will help guide the development of preventive strategies and governmental actions for more effective management of NCDs in the Amazon area." @default.
- W2891918534 created "2018-09-27" @default.
- W2891918534 creator A5007603737 @default.
- W2891918534 creator A5016754764 @default.
- W2891918534 creator A5019217077 @default.
- W2891918534 creator A5031786968 @default.
- W2891918534 creator A5039194866 @default.
- W2891918534 creator A5048878839 @default.
- W2891918534 creator A5051741661 @default.
- W2891918534 creator A5072834025 @default.
- W2891918534 creator A5073811487 @default.
- W2891918534 creator A5086745623 @default.
- W2891918534 date "2018-09-07" @default.
- W2891918534 modified "2023-10-15" @default.
- W2891918534 title "In the Heart of the Amazon: Noncommunicable Diseases and Apolipoprotein E4 Genotype in the Riverine Population" @default.
- W2891918534 cites W124853917 @default.
- W2891918534 cites W1522109397 @default.
- W2891918534 cites W1785699085 @default.
- W2891918534 cites W1967542384 @default.
- W2891918534 cites W1977954026 @default.
- W2891918534 cites W1982970844 @default.
- W2891918534 cites W1992894593 @default.
- W2891918534 cites W2008662532 @default.
- W2891918534 cites W2010656137 @default.
- W2891918534 cites W2027022209 @default.
- W2891918534 cites W2032132732 @default.
- W2891918534 cites W2035345168 @default.
- W2891918534 cites W2044230655 @default.
- W2891918534 cites W2046493598 @default.
- W2891918534 cites W2047146940 @default.
- W2891918534 cites W2061855119 @default.
- W2891918534 cites W2065859331 @default.
- W2891918534 cites W2078052020 @default.
- W2891918534 cites W2079236205 @default.
- W2891918534 cites W2082038548 @default.
- W2891918534 cites W2084849098 @default.
- W2891918534 cites W2088050461 @default.
- W2891918534 cites W2090656314 @default.
- W2891918534 cites W2097178717 @default.
- W2891918534 cites W2100966582 @default.
- W2891918534 cites W2101254128 @default.
- W2891918534 cites W2110251329 @default.
- W2891918534 cites W2112979391 @default.
- W2891918534 cites W2126387090 @default.
- W2891918534 cites W2130735505 @default.
- W2891918534 cites W2140390561 @default.
- W2891918534 cites W2146732895 @default.
- W2891918534 cites W2148332160 @default.
- W2891918534 cites W2149759833 @default.
- W2891918534 cites W2152154407 @default.
- W2891918534 cites W2157540911 @default.
- W2891918534 cites W2158256604 @default.
- W2891918534 cites W2168195699 @default.
- W2891918534 cites W2184347234 @default.
- W2891918534 cites W2257477126 @default.
- W2891918534 cites W2287859856 @default.
- W2891918534 cites W2298852101 @default.
- W2891918534 cites W2371024281 @default.
- W2891918534 cites W2416854880 @default.
- W2891918534 cites W2474812513 @default.
- W2891918534 cites W2560328470 @default.
- W2891918534 cites W2560395594 @default.
- W2891918534 cites W2594522565 @default.
- W2891918534 cites W2755420867 @default.
- W2891918534 cites W2756852269 @default.
- W2891918534 cites W2758073366 @default.
- W2891918534 cites W2768267412 @default.
- W2891918534 cites W2789777688 @default.
- W2891918534 cites W2883278443 @default.
- W2891918534 cites W2887744195 @default.
- W2891918534 cites W4213156113 @default.
- W2891918534 cites W4255720630 @default.
- W2891918534 doi "https://doi.org/10.3390/ijerph15091957" @default.
- W2891918534 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6165059" @default.
- W2891918534 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30205523" @default.
- W2891918534 hasPublicationYear "2018" @default.
- W2891918534 type Work @default.
- W2891918534 sameAs 2891918534 @default.
- W2891918534 citedByCount "17" @default.
- W2891918534 countsByYear W28919185342019 @default.
- W2891918534 countsByYear W28919185342020 @default.
- W2891918534 countsByYear W28919185342021 @default.
- W2891918534 countsByYear W28919185342022 @default.
- W2891918534 countsByYear W28919185342023 @default.
- W2891918534 crossrefType "journal-article" @default.
- W2891918534 hasAuthorship W2891918534A5007603737 @default.
- W2891918534 hasAuthorship W2891918534A5016754764 @default.
- W2891918534 hasAuthorship W2891918534A5019217077 @default.
- W2891918534 hasAuthorship W2891918534A5031786968 @default.
- W2891918534 hasAuthorship W2891918534A5039194866 @default.
- W2891918534 hasAuthorship W2891918534A5048878839 @default.
- W2891918534 hasAuthorship W2891918534A5051741661 @default.
- W2891918534 hasAuthorship W2891918534A5072834025 @default.
- W2891918534 hasAuthorship W2891918534A5073811487 @default.
- W2891918534 hasAuthorship W2891918534A5086745623 @default.
- W2891918534 hasBestOaLocation W28919185341 @default.
- W2891918534 hasConcept C104317684 @default.
- W2891918534 hasConcept C134018914 @default.