SemOpenAlex |

SemOpenAlex

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891920117> ?p ?o ?g. }

Showing items 1 to 100 of ±109 with 100 items per page.

W2891920117 endingPage "152" @default.
W2891920117 startingPage "141" @default.
W2891920117 abstract "As robust osteoinductive cytokines, bone morphogenetic proteins (BMPs) play a significant role in bone tissue engineering. Constituted of two different polypeptides, heterodimeric BMPs are more effective than the homodimers in bone formation. While most studies focused on the murine cell lines, such as murine preosteoblasts MC3T3-E1, the role of heterodimeric BMPs in the osteogenic differentiation of human cells remains uncertain, which hinders their application to practical treatment. In this study, we compared the osteoinductive effects of BMP-2/7 heterodimer in human adipose-derived stem cells (hASCs) with their homodimers BMP-2 and BMP-7, in which MC3T3-E1 cells were utilized as a positive control. The results indicated that BMP-2/7 was not a stronger inducer during the osteogenic differentiation of hASCs as that for MC3T3-E1, and extracellular-signal-regulated kinase signaling played a role in the different effects of BMP-2/7 between hASCs and MC3T3-E1. Our study demonstrates the osteoinductive effects of heterodimeric BMP-2/7 present in a cell-specific pattern and cautions should be taken when applying heterodimeric BMP-2/7 to clinical practice." @default.
W2891920117 created "2018-09-27" @default.
W2891920117 creator A5005359963 @default.
W2891920117 creator A5024238293 @default.
W2891920117 creator A5030458072 @default.
W2891920117 creator A5045899101 @default.
W2891920117 creator A5055151897 @default.
W2891920117 creator A5064703568 @default.
W2891920117 creator A5068275209 @default.
W2891920117 creator A5071033697 @default.
W2891920117 date "2018-07-04" @default.
W2891920117 modified "2023-10-10" @default.
W2891920117 title "Heterodimeric BMP-2/7 exhibits different osteoinductive effects in human and murine cells" @default.
W2891920117 cites W1607413909 @default.
W2891920117 cites W1920665823 @default.
W2891920117 cites W1966133570 @default.
W2891920117 cites W1968521370 @default.
W2891920117 cites W1968822620 @default.
W2891920117 cites W1986993718 @default.
W2891920117 cites W1991912865 @default.
W2891920117 cites W1992104196 @default.
W2891920117 cites W1996176602 @default.
W2891920117 cites W2000973590 @default.
W2891920117 cites W2013039703 @default.
W2891920117 cites W2016126884 @default.
W2891920117 cites W2021594371 @default.
W2891920117 cites W2033954341 @default.
W2891920117 cites W2035653659 @default.
W2891920117 cites W2058104849 @default.
W2891920117 cites W2060709143 @default.
W2891920117 cites W2066384748 @default.
W2891920117 cites W2067423055 @default.
W2891920117 cites W2071251725 @default.
W2891920117 cites W2072314948 @default.
W2891920117 cites W2079268771 @default.
W2891920117 cites W2107503723 @default.
W2891920117 cites W2112903125 @default.
W2891920117 cites W2117054621 @default.
W2891920117 cites W2121759639 @default.
W2891920117 cites W2156124926 @default.
W2891920117 cites W2156682347 @default.
W2891920117 cites W2164961459 @default.
W2891920117 cites W2328407821 @default.
W2891920117 cites W2624215864 @default.
W2891920117 doi "https://doi.org/10.1080/08977194.2018.1477139" @default.
W2891920117 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30238816" @default.
W2891920117 hasPublicationYear "2018" @default.
W2891920117 type Work @default.
W2891920117 sameAs 2891920117 @default.
W2891920117 citedByCount "3" @default.
W2891920117 countsByYear W28919201172020 @default.
W2891920117 countsByYear W28919201172021 @default.
W2891920117 countsByYear W28919201172023 @default.
W2891920117 crossrefType "journal-article" @default.
W2891920117 hasAuthorship W2891920117A5005359963 @default.
W2891920117 hasAuthorship W2891920117A5024238293 @default.
W2891920117 hasAuthorship W2891920117A5030458072 @default.
W2891920117 hasAuthorship W2891920117A5045899101 @default.
W2891920117 hasAuthorship W2891920117A5055151897 @default.
W2891920117 hasAuthorship W2891920117A5064703568 @default.
W2891920117 hasAuthorship W2891920117A5068275209 @default.
W2891920117 hasAuthorship W2891920117A5071033697 @default.
W2891920117 hasConcept C104317684 @default.
W2891920117 hasConcept C125349252 @default.
W2891920117 hasConcept C185592680 @default.
W2891920117 hasConcept C202751555 @default.
W2891920117 hasConcept C28328180 @default.
W2891920117 hasConcept C30352789 @default.
W2891920117 hasConcept C31507581 @default.
W2891920117 hasConcept C49892992 @default.
W2891920117 hasConcept C54355233 @default.
W2891920117 hasConcept C55493867 @default.
W2891920117 hasConcept C86803240 @default.
W2891920117 hasConcept C95444343 @default.
W2891920117 hasConceptScore W2891920117C104317684 @default.
W2891920117 hasConceptScore W2891920117C125349252 @default.
W2891920117 hasConceptScore W2891920117C185592680 @default.
W2891920117 hasConceptScore W2891920117C202751555 @default.
W2891920117 hasConceptScore W2891920117C28328180 @default.
W2891920117 hasConceptScore W2891920117C30352789 @default.
W2891920117 hasConceptScore W2891920117C31507581 @default.
W2891920117 hasConceptScore W2891920117C49892992 @default.
W2891920117 hasConceptScore W2891920117C54355233 @default.
W2891920117 hasConceptScore W2891920117C55493867 @default.
W2891920117 hasConceptScore W2891920117C86803240 @default.
W2891920117 hasConceptScore W2891920117C95444343 @default.
W2891920117 hasFunder F4320321001 @default.
W2891920117 hasIssue "3-4" @default.
W2891920117 hasLocation W28919201171 @default.
W2891920117 hasLocation W28919201172 @default.
W2891920117 hasOpenAccess W2891920117 @default.
W2891920117 hasPrimaryLocation W28919201171 @default.
W2891920117 hasRelatedWork W1991895340 @default.
W2891920117 hasRelatedWork W1997480784 @default.
W2891920117 hasRelatedWork W2352339725 @default.
W2891920117 hasRelatedWork W2518796918 @default.
W2891920117 hasRelatedWork W2752589608 @default.
W2891920117 hasRelatedWork W3027232432 @default.