FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891920875> ?p ?o ?g. }

• W2891920875 abstract "Otitis media is the most common bacterial infection in childhood. Current therapies are limited in the prevention of chronic or recurrent otitis media which leads to increased antibiotic exposure and represents a significant socioeconomic burden. In this study, we delineate the effect of nutritional limitation on the intracellular trafficking pathways used by nontypeable Haemophilus influenzae (NTHI). Moreover, transient limitation of heme-iron led to the development of intracellular bacterial communities that are known to contribute to persistence and recurrence in other diseases. New approaches for therapeutic interventions that reduce the production of intracellular bacterial communities and promote trafficking through the endolysosomal pathway were revealed through the use of pharmacological inhibition of macropinocytosis. This work demonstrates the importance of an intracellular niche for NTHI and provides new approaches for intervention for acute, chronic, and recurring episodes of otitis media." @default.
• W2891920875 created "2018-09-27" @default.
• W2891920875 creator A5012073462 @default.
• W2891920875 creator A5017777082 @default.
• W2891920875 creator A5023986813 @default.
• W2891920875 creator A5036096197 @default.
• W2891920875 creator A5040813688 @default.
• W2891920875 creator A5040832150 @default.
• W2891920875 creator A5050515581 @default.
• W2891920875 creator A5080903509 @default.
• W2891920875 creator A5090392362 @default.
• W2891920875 date "2018-10-31" @default.
• W2891920875 modified "2023-10-16" @default.
• W2891920875 title "Transient Nutrient Deprivation Promotes Macropinocytosis-Dependent Intracellular Bacterial Community Development" @default.
• W2891920875 cites W1614056212 @default.
• W2891920875 cites W1840124877 @default.
• W2891920875 cites W1867882986 @default.
• W2891920875 cites W1870821117 @default.
• W2891920875 cites W1942835246 @default.
• W2891920875 cites W1962974807 @default.
• W2891920875 cites W1970873631 @default.
• W2891920875 cites W1977253956 @default.
• W2891920875 cites W1983540740 @default.
• W2891920875 cites W1992997934 @default.
• W2891920875 cites W1998882814 @default.
• W2891920875 cites W2000568400 @default.
• W2891920875 cites W2004555514 @default.
• W2891920875 cites W2004703377 @default.
• W2891920875 cites W2004748855 @default.
• W2891920875 cites W2005835947 @default.
• W2891920875 cites W2007742983 @default.
• W2891920875 cites W2011545163 @default.
• W2891920875 cites W2015143975 @default.
• W2891920875 cites W2015556811 @default.
• W2891920875 cites W2018066856 @default.
• W2891920875 cites W2021256278 @default.
• W2891920875 cites W2022467415 @default.
• W2891920875 cites W2028249404 @default.
• W2891920875 cites W2033642136 @default.
• W2891920875 cites W2034326093 @default.
• W2891920875 cites W2035643252 @default.
• W2891920875 cites W2036083275 @default.
• W2891920875 cites W2037656756 @default.
• W2891920875 cites W2041918033 @default.
• W2891920875 cites W2043855226 @default.
• W2891920875 cites W2044528912 @default.
• W2891920875 cites W2047140025 @default.
• W2891920875 cites W2049523236 @default.
• W2891920875 cites W2056233239 @default.
• W2891920875 cites W2070429561 @default.
• W2891920875 cites W2074651034 @default.
• W2891920875 cites W2082224404 @default.
• W2891920875 cites W2082408534 @default.
• W2891920875 cites W2084081499 @default.
• W2891920875 cites W2084191014 @default.
• W2891920875 cites W2095929456 @default.
• W2891920875 cites W2096235116 @default.
• W2891920875 cites W2098666638 @default.
• W2891920875 cites W2101507022 @default.
• W2891920875 cites W2101728632 @default.
• W2891920875 cites W2113428334 @default.
• W2891920875 cites W2116065003 @default.
• W2891920875 cites W2116200300 @default.
• W2891920875 cites W2118051267 @default.
• W2891920875 cites W2118410149 @default.
• W2891920875 cites W2122700664 @default.
• W2891920875 cites W2123022837 @default.
• W2891920875 cites W2123854720 @default.
• W2891920875 cites W2124519865 @default.
• W2891920875 cites W2124959265 @default.
• W2891920875 cites W2125688061 @default.
• W2891920875 cites W2128739112 @default.
• W2891920875 cites W2134190834 @default.
• W2891920875 cites W2135373826 @default.
• W2891920875 cites W2135444075 @default.
• W2891920875 cites W2135973974 @default.
• W2891920875 cites W2138406202 @default.
• W2891920875 cites W2139845218 @default.
• W2891920875 cites W2144098483 @default.
• W2891920875 cites W2152718829 @default.
• W2891920875 cites W2153525651 @default.
• W2891920875 cites W2155979125 @default.
• W2891920875 cites W2156107720 @default.
• W2891920875 cites W2171226149 @default.
• W2891920875 cites W2218615501 @default.
• W2891920875 cites W2314723537 @default.
• W2891920875 cites W2339829243 @default.
• W2891920875 cites W2417411065 @default.
• W2891920875 cites W2461789249 @default.
• W2891920875 cites W2500164718 @default.
• W2891920875 cites W2730794648 @default.
• W2891920875 cites W2761887549 @default.
• W2891920875 cites W4294316044 @default.
• W2891920875 doi "https://doi.org/10.1128/msphere.00286-18" @default.
• W2891920875 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6135960" @default.
• W2891920875 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30209128" @default.
• W2891920875 hasPublicationYear "2018" @default.
• W2891920875 type Work @default.
• W2891920875 sameAs 2891920875 @default.
• W2891920875 citedByCount "8" @default.

• next