FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891930107> ?p ?o ?g. }

• W2891930107 endingPage "118" @default.
• W2891930107 startingPage "111" @default.
• W2891930107 abstract "To assess the effect of different intraoperative blood pressure targets on the development of POCD and test the feasibility of a larger trial. Randomized controlled pilot trial. Perioperative care in a tertiary care teaching hospital with outpatient follow-up. One hundred one patients aged ≥75 years with ASA physical status <4, undergoing elective, non-cardiac surgery under general anesthesia and 33 age-matched healthy controls. Randomization to a personalized intraoperative blood pressure target, mean arterial pressure (MAP) ≥ 90% of preoperative values (Target group), or to a more liberal intraoperative blood pressure management (No-Target group). Strategies to reach intraoperative blood pressure target were at discretion of anesthesiologists. An experienced neuropsychologist performed a validated battery of neurocognitive tests preoperatively and 3 months after surgery. Incidence of POCD at three months and postoperative delirium were assessed. Intraoperative time spent with MAP ≥ 90% of preoperative values, recruitment and drop-out rate at 3 months were feasibility outcomes. The Target group spent a higher percentage of intraoperative time with MAP ≥90% of preoperative values (65 ± 25% vs. 49 ± 28%, p < 0.01). Incidence of POCD (11% vs. 7%, relative risk 1.52; 95% CI, 0.41 to 6.3; p = 0.56) and delirium (6% vs. 14%, relative risk, 0.44; 95% CI, 0.12 to 1.60; p = 0.21) did not differ between groups. No correlation was found between intraoperative hypotension and postoperative cognitive performance (p = 0.75) or delirium (p = 0.19). Recruitment rate was of 6 patients/month (95% confidential interval (CI), 5 to 7) and drop-out rate at 3 months was 24% (95% CI, 14 to 33%). Intraoperative hypotension did not correlate with postoperative cognitive dysfunction or delirium occurrence in elderly patients undergoing general anesthesia for non-cardiac surgery. A multicenter randomized controlled trial is needed in order to confirm the effect of intraoperative blood pressure on the development of POCD. NCT02428062 www.clinicaltrials.gov." @default.
• W2891930107 created "2018-09-27" @default.
• W2891930107 creator A5006917212 @default.
• W2891930107 creator A5014932370 @default.
• W2891930107 creator A5019625542 @default.
• W2891930107 creator A5038478502 @default.
• W2891930107 creator A5041212080 @default.
• W2891930107 creator A5042363389 @default.
• W2891930107 creator A5045215148 @default.
• W2891930107 creator A5045595770 @default.
• W2891930107 creator A5065875097 @default.
• W2891930107 creator A5069532601 @default.
• W2891930107 creator A5069641703 @default.
• W2891930107 creator A5080383943 @default.
• W2891930107 creator A5084652949 @default.
• W2891930107 creator A5084918409 @default.
• W2891930107 date "2019-02-01" @default.
• W2891930107 modified "2023-09-27" @default.
• W2891930107 title "Intraoperative hypotension is not associated with postoperative cognitive dysfunction in elderly patients undergoing general anesthesia for surgery: results of a randomized controlled pilot trial" @default.
• W2891930107 cites W1503825389 @default.
• W2891930107 cites W1546425365 @default.
• W2891930107 cites W1964700173 @default.
• W2891930107 cites W1966653619 @default.
• W2891930107 cites W1969932196 @default.
• W2891930107 cites W1972731954 @default.
• W2891930107 cites W1972911854 @default.
• W2891930107 cites W1976233956 @default.
• W2891930107 cites W2000366267 @default.
• W2891930107 cites W2004284087 @default.
• W2891930107 cites W2016928060 @default.
• W2891930107 cites W2039600289 @default.
• W2891930107 cites W2082578146 @default.
• W2891930107 cites W2083990390 @default.
• W2891930107 cites W2097185074 @default.
• W2891930107 cites W2103545765 @default.
• W2891930107 cites W2104117223 @default.
• W2891930107 cites W2112686543 @default.
• W2891930107 cites W2138355641 @default.
• W2891930107 cites W2139090108 @default.
• W2891930107 cites W2149615621 @default.
• W2891930107 cites W2156100110 @default.
• W2891930107 cites W2159813665 @default.
• W2891930107 cites W2161900026 @default.
• W2891930107 cites W2162055755 @default.
• W2891930107 cites W2164059021 @default.
• W2891930107 cites W2166809793 @default.
• W2891930107 cites W2176720133 @default.
• W2891930107 cites W2586426771 @default.
• W2891930107 cites W2757139046 @default.
• W2891930107 cites W2790769651 @default.
• W2891930107 doi "https://doi.org/10.1016/j.jclinane.2018.09.021" @default.
• W2891930107 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30243062" @default.
• W2891930107 hasPublicationYear "2019" @default.
• W2891930107 type Work @default.
• W2891930107 sameAs 2891930107 @default.
• W2891930107 citedByCount "43" @default.
• W2891930107 countsByYear W28919301072019 @default.
• W2891930107 countsByYear W28919301072020 @default.
• W2891930107 countsByYear W28919301072021 @default.
• W2891930107 countsByYear W28919301072022 @default.
• W2891930107 countsByYear W28919301072023 @default.
• W2891930107 crossrefType "journal-article" @default.
• W2891930107 hasAuthorship W2891930107A5006917212 @default.
• W2891930107 hasAuthorship W2891930107A5014932370 @default.
• W2891930107 hasAuthorship W2891930107A5019625542 @default.
• W2891930107 hasAuthorship W2891930107A5038478502 @default.
• W2891930107 hasAuthorship W2891930107A5041212080 @default.
• W2891930107 hasAuthorship W2891930107A5042363389 @default.
• W2891930107 hasAuthorship W2891930107A5045215148 @default.
• W2891930107 hasAuthorship W2891930107A5045595770 @default.
• W2891930107 hasAuthorship W2891930107A5065875097 @default.
• W2891930107 hasAuthorship W2891930107A5069532601 @default.
• W2891930107 hasAuthorship W2891930107A5069641703 @default.
• W2891930107 hasAuthorship W2891930107A5080383943 @default.
• W2891930107 hasAuthorship W2891930107A5084652949 @default.
• W2891930107 hasAuthorship W2891930107A5084918409 @default.
• W2891930107 hasBestOaLocation W28919301072 @default.
• W2891930107 hasConcept C118552586 @default.
• W2891930107 hasConcept C126322002 @default.
• W2891930107 hasConcept C141071460 @default.
• W2891930107 hasConcept C168563851 @default.
• W2891930107 hasConcept C169900460 @default.
• W2891930107 hasConcept C177713679 @default.
• W2891930107 hasConcept C204243189 @default.
• W2891930107 hasConcept C2776452961 @default.
• W2891930107 hasConcept C2777953023 @default.
• W2891930107 hasConcept C2779753318 @default.
• W2891930107 hasConcept C2780043718 @default.
• W2891930107 hasConcept C31174226 @default.
• W2891930107 hasConcept C42219234 @default.
• W2891930107 hasConcept C71924100 @default.
• W2891930107 hasConcept C84393581 @default.
• W2891930107 hasConceptScore W2891930107C118552586 @default.
• W2891930107 hasConceptScore W2891930107C126322002 @default.
• W2891930107 hasConceptScore W2891930107C141071460 @default.
• W2891930107 hasConceptScore W2891930107C168563851 @default.
• W2891930107 hasConceptScore W2891930107C169900460 @default.
• W2891930107 hasConceptScore W2891930107C177713679 @default.

• next