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• W2891938033 abstract "INTRODUCTION:The twentieth century saw unparalleled increase in lifeexpectancy and a major shift in the cause of illness and death throughoutthe world. During this transition cardiovascular disease became the mostcommon cause of death worldwide. A century ago CVD accounted forless than 10% of all deaths. Today it accounts for approximately 30% ofdeaths worldwide including nearly 40% in high-income countries and28% in low and middle-income countries. Driven by industrialization andassociated lifestyle changes, this ongoing transition is occurring aroundthe world among all races, ethnic groups and cultures at an even fasterrate than last century.Based on data from Framingham heart study, the lifetime risk ofdeveloping symptomatic CAD after age forty is 49% for men and 32%for women. The World Health Organization has estimated that by 2020,the global number of deaths from CAD will have risen from 7.2 millionin 2002 to 11.1 million. The evaluation of IHD in women presents aunique and sometimes difficult challenge for clinicians, owing to thedifference in symptoms, clinical features and mortality as compared tomen. The diagnosis and treatment of CHD have been primarily based onresearch conducted in men, either excluding women entirely or includinglimited number of women. The use of traditional risk factors assessmentwas limited in prediction of CAD in women. The compendium ofcoronary heart disease data indicate that current research and strategydevelopment must focus on gender-specific issues in order to address thesocietal burden and costs related to these demographic shifts in IHD thatplace women in the majority of those impacted. This significant burden ofthe disease in women places unique diagnostic, treatment, and financialencumbrances on our society that are only further intensified by a lack ofpublic awareness about the disease on the part of patients and cliniciansalike. This societal burden of the disease is, in part, related to our poorunderstanding of gender-specific pathophysiologic differences in thepresentation and prognosis of IHD and the paucity of diagnostic andtreatment guidelines tailored to phenotypic differences in women.This study is to analyse the clinical presentation, complicationsand outcome in those women who presented with myocardial infarction.AIM OF THE STUDY:1. To analyse the various risk factors in women with acute myocardialinfarction.2. To study the presenting features, site of infarction andcomplications of acute myocardial infarction in women.3. To study the outcome in women with acute myocardial infarctionadmitted to coronary care unit.MATERIALS AND METHODS:Hundred women admitted with acute myocardial infarction incoronary care unit of Government General Hospital were randomly selected forthe study for a period of one year from July 2008 to June 2009.Persons included in the study were informed about the aim of thestudy and consent was obtained.Information like age, symptoms, time interval to reach hospital,associated comorbid conditions such as hypertension, diabetes, coronaryartery disease, family history, menstrual status, complete clinicalexamination and treatment details were collected.Investigations like electrocardiogram, echocardiogram, renalfunction test, lipid profile were also done.All the patients were followed up during their hospital stay and theoutcome recorded.The collected data were analysed with regards to age ofpresentation, menstrual status, symptoms, time to reach hospital since theonset of symptoms, severity of clinical presentation according to Killip’sclassification, electrocardiographic changes and echocardiographicchanges with in hospital outcome.Pump failure is now the primary cause of in hospital death due toSTEMI. The extent of infarction correlates well with the degree of pumpfailure and with mortality both early and later2.OBSERVATIONS:Among the hundred women selected for the study, 21 were in theage group of 50 and below, 33 were in the 51 to 60 age group, 22 were inthe 61 to 70 age group and 24 were in the age group of above 70. This isshown in Table 1 and Figure 1. The mean age is 60.97 and the range is 35– 85.CONCLUSION:1. Women with advanced age have a poorer outcome.2. Women clinically present with atypical symptoms that has resulted ina significant delay to reach treatment centre.3. In hospital mortality is directly related to atypical symptoms, delay inreaching the hospital and co morbidities." @default.
• W2891938033 created "2018-09-27" @default.
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• W2891938033 date "2010-03-01" @default.
• W2891938033 modified "2023-09-26" @default.
• W2891938033 title "A Study on Acute Myocardial Infarction in Women" @default.
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