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- W2891982137 abstract "Dietary sodium is an important trigger for hypertension and humans show a heterogeneous blood pressure response to salt intake. The precise mechanisms for this have not been fully explained although renal sodium handling has traditionally been considered to play a central role.Animal studies have shown that dietary salt loading results in non-osmotic sodium accumulation via glycosaminoglycans and lymphangiogenesis in skin mediated by vascular endothelial growth factor-C, both processes attenuating the rise in BP. Studies in humans have shown that skin could be a buffer for sodium and that skin sodium could be a marker of hypertension and salt sensitivity. Skin sodium storage could represent an additional system influencing the response to salt load and blood pressure in humans." @default.
- W2891982137 created "2018-09-27" @default.
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- W2891982137 date "2018-09-13" @default.
- W2891982137 modified "2023-10-14" @default.
- W2891982137 title "Skin Sodium and Hypertension: a Paradigm Shift?" @default.
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- W2891982137 doi "https://doi.org/10.1007/s11906-018-0892-9" @default.
- W2891982137 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6153561" @default.
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