FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2891995304> ?p ?o ?g. }

• W2891995304 endingPage "519" @default.
• W2891995304 startingPage "511" @default.
• W2891995304 abstract "Introduction: Intermittent 1-34 parathyroid hormone (iPTH) administration, a bone-forming treatment, is widely used as a therapy for severe osteoporosis. It can only be used for a maximum of 24 mo and must be followed by an antiresorptive drug to retain the new formed tissue. Mechanical load, in the form of low-intensity and high-frequency vibration, has received considerable attention due to its ability to prevent bone loss. Aim: To investigate the ability of whole body mechanical vibration (MV) to potentiate the anabolic effects of iPTH and to inhibit bone resorption following discontinuation of iPTH treatment in estrogen-deficient rats. Methodology: Fifty-four 6-month-old female Wistar rats were ovariectomized (OVX) or sham-operated. After 5 mo, they were divided into 7 groups: Sham – non-OVX; Control – OVX, vehicle for 60 d; MV – OVX, submitted to MV for 60 d; PTH60d – OVX, injected with iPTH for 60 d; PTH+MV – OVX, injected with iPTH combined with MV for 60 d; PTH30d – OVX, injected with iPTH for 30 d, and untreated for 30 d; PTH30d/MV30d – OVX, injected with iPTH for 30 d, followed by MV for 30 d. Bone mineral density (BMD) and body composition (lean mass and fat) were evaluated at OVX (T0), the beginning (T1), and at the end (T2) of treatments by dual X-ray absorptiometry (DXA). Femurs were processed for histomorphometry (bone volume - BV/TV and cortical thickness - Ct.Th) and tibias for biomechanical test. Results: Body composition and BMD were similar among the groups at T0. In T2, MV presented higher fat than other groups (except PTH60d) and PTH30d/MV30d showed greater lean mass than Control. At T1, Sham presented the highest BMD, but between T1 vs T2 there was an increase in all iPTH-treated groups. At T2, BMD was higher in PTH60d and PTH+MV than in the Control and MV groups. The highest BV/TV was observed in the PTH+MV group, followed by PTH60d. Cortical thickness was increased in PTH60d and PTH+MV compared to Sham. Vibration applied post-iPTH (PTH30d/MV30d) improved the force at failure in tibias when compared to Sham and Control groups. Conclusion: MV potentiated iPTH anabolic effects in cancellous bone; however, MV was unable to maintain bone mass after stopping iPTH in ovariectomized rats." @default.
• W2891995304 created "2018-09-27" @default.
• W2891995304 creator A5022624074 @default.
• W2891995304 creator A5027489883 @default.
• W2891995304 creator A5031737005 @default.
• W2891995304 creator A5070256085 @default.
• W2891995304 creator A5078075596 @default.
• W2891995304 creator A5082017297 @default.
• W2891995304 date "2020-07-01" @default.
• W2891995304 modified "2023-10-13" @default.
• W2891995304 title "Mechanical Vibration Associated With Intermittent PTH Improves Bone Microarchitecture in Ovariectomized Rats" @default.
• W2891995304 cites W1606867770 @default.
• W2891995304 cites W1938513264 @default.
• W2891995304 cites W1965535050 @default.
• W2891995304 cites W1965597148 @default.
• W2891995304 cites W1965696823 @default.
• W2891995304 cites W1982195212 @default.
• W2891995304 cites W1983046937 @default.
• W2891995304 cites W2008933264 @default.
• W2891995304 cites W2012719787 @default.
• W2891995304 cites W2013599591 @default.
• W2891995304 cites W2039602566 @default.
• W2891995304 cites W2040271062 @default.
• W2891995304 cites W2043404755 @default.
• W2891995304 cites W2045031118 @default.
• W2891995304 cites W2080102311 @default.
• W2891995304 cites W2080818296 @default.
• W2891995304 cites W2096425957 @default.
• W2891995304 cites W2101680622 @default.
• W2891995304 cites W2110396808 @default.
• W2891995304 cites W2115615294 @default.
• W2891995304 cites W2128849535 @default.
• W2891995304 cites W2129472618 @default.
• W2891995304 cites W2165247178 @default.
• W2891995304 cites W2169791814 @default.
• W2891995304 cites W2222106346 @default.
• W2891995304 cites W2267824590 @default.
• W2891995304 cites W2335178464 @default.
• W2891995304 cites W2473277322 @default.
• W2891995304 cites W2544386575 @default.
• W2891995304 cites W2589483800 @default.
• W2891995304 cites W2792470187 @default.
• W2891995304 doi "https://doi.org/10.1016/j.jocd.2018.09.003" @default.
• W2891995304 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30327242" @default.
• W2891995304 hasPublicationYear "2020" @default.
• W2891995304 type Work @default.
• W2891995304 sameAs 2891995304 @default.
• W2891995304 citedByCount "3" @default.
• W2891995304 countsByYear W28919953042019 @default.
• W2891995304 countsByYear W28919953042023 @default.
• W2891995304 crossrefType "journal-article" @default.
• W2891995304 hasAuthorship W2891995304A5022624074 @default.
• W2891995304 hasAuthorship W2891995304A5027489883 @default.
• W2891995304 hasAuthorship W2891995304A5031737005 @default.
• W2891995304 hasAuthorship W2891995304A5070256085 @default.
• W2891995304 hasAuthorship W2891995304A5078075596 @default.
• W2891995304 hasAuthorship W2891995304A5082017297 @default.
• W2891995304 hasConcept C1008401 @default.
• W2891995304 hasConcept C126322002 @default.
• W2891995304 hasConcept C126894567 @default.
• W2891995304 hasConcept C134018914 @default.
• W2891995304 hasConcept C146562846 @default.
• W2891995304 hasConcept C2776541429 @default.
• W2891995304 hasConcept C2776886416 @default.
• W2891995304 hasConcept C2777083390 @default.
• W2891995304 hasConcept C2777164284 @default.
• W2891995304 hasConcept C2781208988 @default.
• W2891995304 hasConcept C2781440623 @default.
• W2891995304 hasConcept C519063684 @default.
• W2891995304 hasConcept C673006 @default.
• W2891995304 hasConcept C71924100 @default.
• W2891995304 hasConcept C8264082 @default.
• W2891995304 hasConceptScore W2891995304C1008401 @default.
• W2891995304 hasConceptScore W2891995304C126322002 @default.
• W2891995304 hasConceptScore W2891995304C126894567 @default.
• W2891995304 hasConceptScore W2891995304C134018914 @default.
• W2891995304 hasConceptScore W2891995304C146562846 @default.
• W2891995304 hasConceptScore W2891995304C2776541429 @default.
• W2891995304 hasConceptScore W2891995304C2776886416 @default.
• W2891995304 hasConceptScore W2891995304C2777083390 @default.
• W2891995304 hasConceptScore W2891995304C2777164284 @default.
• W2891995304 hasConceptScore W2891995304C2781208988 @default.
• W2891995304 hasConceptScore W2891995304C2781440623 @default.
• W2891995304 hasConceptScore W2891995304C519063684 @default.
• W2891995304 hasConceptScore W2891995304C673006 @default.
• W2891995304 hasConceptScore W2891995304C71924100 @default.
• W2891995304 hasConceptScore W2891995304C8264082 @default.
• W2891995304 hasIssue "3" @default.
• W2891995304 hasLocation W28919953041 @default.
• W2891995304 hasOpenAccess W2891995304 @default.
• W2891995304 hasPrimaryLocation W28919953041 @default.
• W2891995304 hasRelatedWork W2070612534 @default.
• W2891995304 hasRelatedWork W2093572014 @default.
• W2891995304 hasRelatedWork W2318452431 @default.
• W2891995304 hasRelatedWork W2385939269 @default.
• W2891995304 hasRelatedWork W2386420363 @default.
• W2891995304 hasRelatedWork W2393570286 @default.
• W2891995304 hasRelatedWork W2398068415 @default.

• next