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- W2891999232 abstract "Alectinib can cause rare, but severe hypersensitivity. The cross-reactivity between different ALK inhibitors is unknown and desensitization is the only reported management. We hereby report the first case of severe delayed hypersensitivity developed in a lung cancer patient treated by alectinib, who was successfully managed by switching to brigatinib, another ALK inhibitor. The patient achieved excellent anti-tumor response to brigatinib. Our case provides an alternative and safe strategy in patients with alectinib-related hypersensitivity." @default.
- W2891999232 created "2018-09-27" @default.
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- W2891999232 date "2018-09-01" @default.
- W2891999232 modified "2023-09-25" @default.
- W2891999232 title "Hypersensitivity in ALK-positive lung cancers exposed to ALK inhibitors: a case of successful switch to an alternative ALK inhibitor and systematic review of the literature" @default.
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- W2891999232 doi "https://doi.org/10.2147/lctt.s173948" @default.
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